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We employed a daily limited\u2010access ethanol intake model called Drinking in the Dark (DID) to assess the effects of voluntary maternal binge\u2010like ethanol intake on the developing mouse. Evidence suggests that binge exposure may be particularly harmful to the embryo\/fetus, perhaps due to the relatively higher blood ethanol concentrations achieved. Pregnant females had mean daily ethanol intakes ranging from 4.2 to 6.4 g\/kg ethanol over gestation, producing blood ethanol concentrations ranging from 115 to 182 mg\/dL. This level of ethanol intake produced behavioral alterations among adolescent offspring that disappeared by adulthood, including altered sensitivity to ethanol's hypnotic actions. The DID model may provide a useful tool for studying the effects of prenatal ethanol exposure in mice. \u00a9 2008 Wiley Periodicals, Inc. 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