{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:22:45Z","timestamp":1788870165146,"version":"build-2803163510"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,1,28]],"date-time":"2015-01-28T00:00:00Z","timestamp":1422403200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["MH080055"],"award-info":[{"award-number":["MH080055"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR000064"],"award-info":[{"award-number":["UL1TR000064"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Developmental Psychobiology"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>\n                      Repetitive behaviors are diagnostic for autism spectrum disorders, common in related neurodevelopmental disorders, and normative in typical development. In order to identify factors that mediate repetitive behavior development, it is necessary to characterize the expression of these behaviors from an early age. Extending previous findings, we characterized further the ontogeny of stereotyped motor behavior both in terms of frequency and temporal organization in deer mice. A three group trajectory model provided a good fit to the frequencies of stereotyped behavior across eight developmental time points. Group based trajectory analysis using a measure of temporal organization of stereotyped behavior also resulted in a three group solution. Additionally, as the frequency of stereotyped behavior increased with age, the temporal distribution of stereotyped responses became increasingly regular or organized indicating a strong association between these measures. Classification tree and principal components analysis showed that accurate classification of trajectory group could be done with fewer observations. This ability to identify trajectory group membership earlier in development allows for examination of a wide range of variables, both experiential and biological, to determine their impact on altering the expected trajectory of repetitive behavior across development. Such studies would have important implications for treatment efforts in neurodevelopmental disorders such as autism. \u00a9 2015\n                      <jats:italic>Wiley Periodicals, Inc<\/jats:italic>\n                      . Dev Psychobiol 57: 201\u2013211, 2015.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dev.21279","type":"journal-article","created":{"date-parts":[[2015,1,29]],"date-time":"2015-01-29T00:06:38Z","timestamp":1422489998000},"page":"201-211","source":"Crossref","is-referenced-by-count":14,"title":["Repetitive motor behavior: Further characterization of development and temporal dynamics"],"prefix":"10.1002","volume":"57","author":[{"given":"Amber M.","family":"Muehlmann","sequence":"first","affiliation":[{"name":"Department of Psychiatry and McKnight Brain Institute University of Florida FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolay","family":"Bliznyuk","sequence":"additional","affiliation":[{"name":"Department of Statistics University of Florida FL"},{"name":"Department of Agricultural and Biological Engineering FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac","family":"Duerr","sequence":"additional","affiliation":[{"name":"Department of Statistics University of Florida FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark H.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and McKnight Brain Institute University of Florida FL"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","DOI":"10.4172\/2165-7890.S1-006","volume-title":"Modeling restricted repetitive behavior in animals","author":"Bechard A.","year":"2012"},{"issue":"4","key":"e_1_2_6_3_1","first-page":"407","article-title":"Litter size predicts adult stereotypic behavior in female laboratory mice","volume":"51","author":"Bechard A.","year":"2012","journal-title":"Journal of the American Association for Laboratory Animal Science"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1005596502855"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2012.11.016"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-8624.1997.tb01925.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0387-7604(99)00059-5"},{"key":"e_1_2_6_8_1","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780198521600.003.0009","volume-title":"Stereotyped behaviour in madness and in health","author":"Frith C. D.","year":"1990"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-009-0810-8"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-84858-7"},{"key":"e_1_2_6_11_1","volume-title":"Applied Multivariate Statistical Analysis","author":"Johnson R. A.","year":"2002"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0049124106292364"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0049124101029003005"},{"key":"e_1_2_6_14_1","article-title":"Changes in the development of striatum are involved in repetitive behavior","author":"Langen M.","year":"2013","journal-title":"Biological Psychiatry"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199001000-00004"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2779(1998)4:2<80::AID-MRDD4>3.0.CO;2-0"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-011-1356-0"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bandc.2006.02.007"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-2302(200009)37:2<100::AID-DEV5>3.0.CO;2-6"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2004.08.003"},{"key":"e_1_2_6_21_1","volume-title":"R: A language and environment for statistical computing","year":"2008"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579409990265"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-7610.00472"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spen.2009.03.008"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.31238"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijdevneu.2011.02.004"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/dev.20477"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-3472(79)90006-X"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/dev.10116"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2003.07.008"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(02)02472-1"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-012-2860-4"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12207"},{"key":"e_1_2_6_34_1","doi-asserted-by":"crossref","DOI":"10.1201\/9781420010404","volume-title":"Generalized Additive Models: An Introduction with R, Chapman & Hall\/CRC","author":"Wood S.","year":"2006"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.1997.tb01616.x"}],"container-title":["Developmental Psychobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdev.21279","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dev.21279","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T17:58:01Z","timestamp":1717696681000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dev.21279"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,28]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1002\/dev.21279"],"URL":"https:\/\/doi.org\/10.1002\/dev.21279","archive":["Portico"],"relation":{},"ISSN":["0012-1630","1098-2302"],"issn-type":[{"value":"0012-1630","type":"print"},{"value":"1098-2302","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,28]]}}}