{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:52:04Z","timestamp":1777449124786,"version":"3.51.4"},"reference-count":42,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T00:00:00Z","timestamp":1560816000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Centro de Investigaci\u00f3n y Estudios Avanzados del Instituto Polit\u00e9cnico Nacional, M\u00e9xico","award":["2018 Annual Budget"],"award-info":[{"award-number":["2018 Annual Budget"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Developmental Psychobiology"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To restore estrus in lactating doe rabbits, nursing was prevented on lactation day 10 and allowed again from day 12 onward. This \u201cbiostimulation\u201d procedure, used to accelerate reproduction, allows kit survival despite a 48\u00a0hr fast. Yet, the consequences of \u201cbiostimulation\u201d on their psychobiological and neuroendocrine development are largely unknown. Therefore, we determined, in adult males and females, tested in the morning or afternoon: corticosteroid secretion (baseline and reactive), sexual behavior, and responses in six tests measuring stress\/anxiety. The latter were not affected by maternal deprivation or time of testing in either sex. The lordosis quotient was reduced in deprived does (relative to controls), an effect eliminated when only non\u2010kins (of both groups) were compared. Deprived males showed altered sexual behavior, evidenced by a large number of mounts not culminating in ejaculation. Corticosterone and cortisol secretion increased (relative to baseline) following i.m. saline in all groups, but the magnitude of the response was affected by maternal deprivation, time of day, and sex. Results indicate that particular behaviors and reactivity to stress have different thresholds regarding the effects of mother\u2013litter separation in early lactation.<\/jats:p>","DOI":"10.1002\/dev.21882","type":"journal-article","created":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T13:06:42Z","timestamp":1560863202000},"page":"988-998","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Long\u2010lasting behavioral and neuroendocrine changes provoked in rabbits by cancelling a single nursing bout in early lactation"],"prefix":"10.1002","volume":"61","author":[{"given":"Hilda L.","family":"Garc\u00eda Fern\u00e1ndez","sequence":"first","affiliation":[{"name":"Centro de Investigaci\u00f3n en Reproducci\u00f3n Animal CINVESTAV\u2010Universidad Aut\u00f3noma de Tlaxcala Tlaxcala M\u00e9xico"},{"name":"Maestr\u00eda en Ciencias Biol\u00f3gicas Universidad Aut\u00f3noma de Tlaxcala Tlaxcala M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David R.","family":"Chavira\u2010Ram\u00edrez","sequence":"additional","affiliation":[{"name":"Departamento de Biolog\u00eda de la Reproducci\u00f3n Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n \u201cSalvador Zubir\u00e1n\u201d Mexico City M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9405-7926","authenticated-orcid":false,"given":"Gabriela","family":"Gonz\u00e1lez\u2010Mariscal","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Reproducci\u00f3n Animal CINVESTAV\u2010Universidad Aut\u00f3noma de Tlaxcala Tlaxcala M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,6,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ejn.14265"},{"key":"e_1_2_6_3_1","first-page":"191","article-title":"Effect of mother\u2013 litter separation on reproductive performance of lactating rabbit females inseminated on day 4 or 11 post\u2010partum","volume":"6","author":"Alvari\u00f1o J. M. R.","year":"1998","journal-title":"World Rabbit Science"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/dev.10134"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anbehav.2005.01.015"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9384(69)90112-7"},{"key":"e_1_2_6_7_1","first-page":"1","article-title":"The reproduction of the wild rabbit, Oryctolagus cuniculus (L.)","volume":"114","author":"Brambell F. W. R.","year":"1944","journal-title":"Journal of Zoology"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2009.09.057"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/dneu.20687"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0002210"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2008.02.013"},{"key":"e_1_2_6_12_1","first-page":"199","article-title":"Effect of mother\u2013litter separation for 24 h, by closing the nestbox or change of cage, on rabbit doe reproduction performance","volume":"6","author":"Castellini C.","year":"1998","journal-title":"World Rabbit Science"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9384(79)90204-X"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2015.11.001"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.applanim.2009.07.005"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20862"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-18-07840.2002"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2011.11.003"},{"key":"e_1_2_6_19_1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/B978-0-12-803592-4.00003-1","volume-title":"Hormones, brain and behavior","author":"Gonz\u00e1lez\u2010Mariscal G.","year":"2017"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2015.05.011"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9384(94)90391-3"},{"key":"e_1_2_6_22_1","first-page":"145","article-title":"Impact of concurrent pregnancy and lactation on maternal nest\u2010building, estradiol and progesterone concentrations in rabbits","volume":"17","author":"Gonz\u00e1lez\u2010Mariscal G.","year":"2009","journal-title":"World Rabbit Science"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-62817-2_6"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-803592-4.00017-1"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2009.10.021"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.4995\/wrs.2012.1034"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-3057(02)00781-5"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2014.140"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1051\/animres:19720111"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2015.05.017"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2010.05.003"},{"key":"e_1_2_6_32_1","volume-title":"The neurobiology of parental behavior","author":"Numan M.","year":"2003"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19860100"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1159\/000441059"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2006.09.013"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(00)00381-8"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2008.07.011"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/dneu.22197"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1186\/1744-9081-7-11"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4530(03)00153-7"},{"key":"e_1_2_6_41_1","first-page":"177","article-title":"Effect of a doe\u2013litter separation on rabbit doe reproductive performance and growth of the young","volume":"7","author":"Theau\u2010Clement M.","year":"1999","journal-title":"World Rabbit Science"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.applanim.2008.12.004"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.4995\/wrs.2012.1082"}],"container-title":["Developmental Psychobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdev.21882","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dev.21882","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dev.21882","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dev.21882","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T07:41:42Z","timestamp":1694245302000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dev.21882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,18]]},"references-count":42,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["10.1002\/dev.21882"],"URL":"https:\/\/doi.org\/10.1002\/dev.21882","archive":["Portico"],"relation":{},"ISSN":["0012-1630","1098-2302"],"issn-type":[{"value":"0012-1630","type":"print"},{"value":"1098-2302","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,18]]},"assertion":[{"value":"2019-01-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}