{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:38:19Z","timestamp":1786977499324,"version":"build-2736575974"},"reference-count":79,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T00:00:00Z","timestamp":1726185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100020780","name":"Lucile Packard Foundation for Children's Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Developmental Psychobiology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Research and theory suggest an important role of neuroendocrine function in emotional development, particularly under conditions of elevated stress. We provide empirical data to clarify associations between alpha\u2010amylase (AA) and cortisol as well as test the differential linkages among AA, cortisol, and symptoms of anxiety, depression, and posttraumatic stress in children. Children recruited from a low\u2010income elevated violence community (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a0100; mean age\u00a0=\u00a010, SD\u00a0=\u00a00.64; 79% Latino; 67% received free or reduced lunch) were assessed on diurnal levels of AA and cortisol along with assessments of anxiety, depression, and posttraumatic stress symptoms (PTSS). Elevated anxiety symptoms were associated with steeper linear slopes of AA with higher levels of AA in the morning but lower levels of AA in the evening. Depression was associated with differential cubic trajectories of AA when PTSSs were included in the model. Anxiety also predicted differential cubic diurnal trends in cortisol, such that greater anxiety symptoms were associated with relatively higher levels of cortisol in the evening. Again, depression symptoms when PTSS were included predicted diurnal cubic trends with elevated depression associated with lower awakening and midday cortisol that reversed to higher evening cortisol compared to youth with fewer self\u2010reported depression symptoms.\n                  <\/jats:p>","DOI":"10.1002\/dev.22549","type":"journal-article","created":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T04:34:47Z","timestamp":1726202087000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Evidence of Differential Prediction of Anxiety and Depression by Diurnal Alpha\u2010Amylase and Cortisol in Development"],"prefix":"10.1002","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4947-0268","authenticated-orcid":false,"given":"Bethany H.","family":"McCurdy","sequence":"first","affiliation":[{"name":"Human Development and Family Studies Iowa State University Ames Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9214-3401","authenticated-orcid":false,"given":"Carl F.","family":"Weems","sequence":"additional","affiliation":[{"name":"Human Development and Family Studies Iowa State University Ames Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Travis","family":"Bradley","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, School of Medicine Stanford University Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Matlow","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, School of Medicine Stanford University Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor G.","family":"Carri\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, School of Medicine Stanford University Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2009.06.011"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2011.07.007"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2017.05.018"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874210601307010007"},{"key":"e_1_2_9_6_1","doi-asserted-by":"crossref","unstructured":"Asia R.2009. \u201cThe Relationship of Level of Traumatic Exposure Perceived Stress and Resilience With Salivary Cortisol and Salivary Alpha\u2010Amylase Diurnal Rhythm in Palestinian Children 10\u201312 Years Exposed to Chronic War Violence.\u201d Diss. 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