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While frequently asymptomatic or not lifestyle limiting, at least 1% of the population has peripheral artery disease of sufficient severity to be limb threatening. To avoid the critical error of failing to diagnose ischaemia, all patients with diabetic foot ulcers and gangrene should routinely undergo physiologic evaluation of foot perfusion. Ankle brachial index is useful when measurable, but may be falsely elevated or not obtainable in as many as 30% of patients with diabetic foot ulcers primarily because of medial calcinosis. Toe pressures and skin perfusion pressures are applicable to such patients. Copyright \u00a9 2016 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/dmrr.2753","type":"journal-article","created":{"date-parts":[[2015,10,12]],"date-time":"2015-10-12T18:15:39Z","timestamp":1444673739000},"page":"239-245","source":"Crossref","is-referenced-by-count":41,"title":["Lower limb ischaemia in patients with diabetic foot ulcers and gangrene: recognition, anatomic patterns and revascularization strategies"],"prefix":"10.1002","volume":"32","author":[{"given":"Joseph L.","family":"Mills","sequence":"first","affiliation":[{"name":"Surgery Baylor College of Medicine Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,1,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2011.10.029"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1358836X0100600i102"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.12.037"},{"issue":"5","key":"e_1_2_6_5_1","first-page":"499","article-title":"Die chirugische Behandlung der peripheren Durchblutungst\u00f6rungen. 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