{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T10:47:50Z","timestamp":1778669270680,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,1,20]],"date-time":"2019-01-20T00:00:00Z","timestamp":1547942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003142","name":"Fonds NutsOhra","doi-asserted-by":"publisher","award":["1002\u2010042"],"award-info":[{"award-number":["1002\u2010042"]}],"id":[{"id":"10.13039\/501100003142","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Metabolism Res"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Current guidelines recommend screening the feet of diabetic subjects with a 10\u2010g monofilament or tuning fork. We investigated which tests and locations on the feet have the best predictive value regarding 1\u2010year ulcer\u2010free survival in diabetic subjects participating in the prospective Rotterdam Diabetic Foot Study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Decision tree analysis was used to predict ulcer\u2010free survival based on responses from individual test locations (monofilaments on 10 sites, vibration sense was tested on both halluces and medial malleoli). Separate trees for patients with and without a history of diabetic foot ulcer (DFU) were developed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Four hundred sixteen subjects (mean [SD] age, 61.8\u00a0years [12.4]; range, 21.6\u201090.2) were measured, of whom 24 developed new DFUs. Three tests exhibited discriminative and predictive properties: testing vibration sense on the medial malleolus and monofilament testing on heel and hallux. The decision tree to predict ulcer\u2010free survival in patients with a history of DFU yielded a sensitivity of 87.0%, which was 99.6% for the tree of patients without a history of DFU.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The findings of this study aids medical decision making by discriminating between high\u2010 and low\u2010risk patients of developing DFU using selective testing on sites with predictive properties.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dmrr.3119","type":"journal-article","created":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T19:32:54Z","timestamp":1545420774000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Predicting ulcer\u2010free survival using the discriminative value of screening test locations"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8137-3076","authenticated-orcid":false,"given":"Willem D.","family":"Rinkel","sequence":"first","affiliation":[{"name":"Department of Plastic, Reconstructive, and Hand surgery Erasmus University Medical Center  Rotterdam the Netherlands"},{"name":"Department of Plastic, Reconstructive, and Hand surgery Franciscus Gasthuis &amp; Vlietland  Rotterdam the Netherlands"},{"name":"Department of Plastic, Reconstructive, and Hand surgery University Medical Center Utrecht (UMCU)  Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark J.W.","family":"van der Oest","sequence":"additional","affiliation":[{"name":"Department of Plastic, Reconstructive, and Hand surgery Erasmus University Medical Center  Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Don A.","family":"Dijkstra","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine\/Centre for Diabetes, Endocrinology and Vascular Medicine Franciscus Gasthuis &amp; Vlietland  Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Castro Cabezas","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine\/Centre for Diabetes, Endocrinology and Vascular Medicine Franciscus Gasthuis &amp; Vlietland  Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Hendrik","family":"Coert","sequence":"additional","affiliation":[{"name":"Department of Plastic, Reconstructive, and Hand surgery Erasmus University Medical Center  Rotterdam the Netherlands"},{"name":"Department of Plastic, Reconstructive, and Hand surgery Franciscus Gasthuis &amp; 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