{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:18:09Z","timestamp":1790680689481,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2020,3,16]],"date-time":"2020-03-16T00:00:00Z","timestamp":1584316800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Metabolism Res"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Diabetic foot disease greatly impacts both affected patients and society, but remains the \u201cCinderella\u201d of diabetes\u2010related complications. However, recent progress in research and guideline development have led to increased awareness of the problem and improved clinical outcomes. Thus, it is time for a shift in global perception of this increasingly prevalent problem. In this special issue, we present 7 up\u2010to\u2010date clinical guidelines and 10 systematic reviews developed by the International Working Group on the Diabetic Foot, together with 17 informative and stimulating related papers. These guidelines offer new recommendations on ulcer classification, diagnosis of infection severity, and vascular assessment, to assist in ulcer risk stratification, diagnosis and interdisciplinary communication. Key developments include providing guidance on methodological assessment of research papers; expanding the evidence base for ulcer treatment by the use of wound products and offloading treatment and suggestions for improving ulcer prevention through technological advances in patient monitoring of risk factors and footwear. The 17 invited papers discuss related topics ranging from stem cell research to patient psychology and describe the way forward in diabetic foot care. While there is much more to learn, the new knowledge of underlying pathways, advancements in diagnosis, treatment and prevention presented in this supplement should help improve outcomes and reduce the great and growing burden of diabetic foot disease.<\/jats:p>","DOI":"10.1002\/dmrr.3249","type":"journal-article","created":{"date-parts":[[2020,3,16]],"date-time":"2020-03-16T09:07:41Z","timestamp":1584349661000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Diabetic foot disease: \u201cThe Times They are A Changin\u2019 \u201d"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8357-9163","authenticated-orcid":false,"given":"Sicco A.","family":"Bus","sequence":"first","affiliation":[{"name":"Amsterdam UMC, University of Amsterdam Rehabilitation Medicine, Amsterdam Movement Sciences Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6420-6046","authenticated-orcid":false,"given":"Jaap J.","family":"van Netten","sequence":"additional","affiliation":[{"name":"Amsterdam UMC, University of Amsterdam Rehabilitation Medicine, Amsterdam Movement Sciences Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4586-2910","authenticated-orcid":false,"given":"Matilde","family":"Monteiro\u2010Soares","sequence":"additional","affiliation":[{"name":"MEDCIDS: Departamento de Medicina da Comunidade Informa\u00e7\u00e3o e Decis\u00e3o em Sa\u00fade &amp; CINTESIS \u2013 Center for Health Technology and Services Research, Faculdade de Medicina da Universidade do Porto Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin A.","family":"Lipsky","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Washington Seattle Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2128-8029","authenticated-orcid":false,"given":"Nicolaas C.","family":"Schaper","sequence":"additional","affiliation":[{"name":"Division of Endocrinology MUMC+, CARIM and CAPHRI Institute Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,3,16]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.13680"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1615439"},{"key":"e_1_2_3_4_1","unstructured":"Time to act: diabetes and foot care. A joint publication of the International Diabetes Federation and the International Working Group on the Diabetic Foot 2005 https:\/\/www.worlddiabetesfoundation.org\/files\/diabetes-and-foot-care-time-act."},{"key":"e_1_2_3_5_1","unstructured":"DylanB.The times they are a\u2010changin\u2019. The times they are a\u2010changin\u2019 (album). Tom Wilson (producer) Columbia Records 1964 track 1."},{"key":"e_1_2_3_6_1","article-title":"An in\u2010depth assessment of diabetes\u2010related lower extremity amputation rates 2000\u20102013 delivered by twenty\u2010one countries for the data collection 2015 of the Organization for Economic Cooperation and Development (OECD)","author":"Carinci F","year":"2019","journal-title":"Acta Diabetol"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-018-4711-2"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3273"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3280"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3276"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3241"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3242"},{"key":"e_1_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3240"},{"key":"e_1_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(17)30438-2"},{"key":"e_1_2_3_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(18)30240-7"},{"key":"e_1_2_3_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3283"},{"key":"e_1_2_3_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3274"},{"key":"e_1_2_3_18_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta19570"},{"key":"e_1_2_3_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3269"},{"issue":"1","key":"e_1_2_3_20_1","doi-asserted-by":"crossref","first-page":"e3234","DOI":"10.1002\/dmrr.3234","article-title":"The future of diabetic foot ulcer prevention: a paradigm shift from stratified healthcare towards personalised medicine","volume":"36","author":"Netten JJ","year":"2020","journal-title":"Diabetes Metab Res Rev"},{"key":"e_1_2_3_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3239"},{"key":"e_1_2_3_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3259"},{"key":"e_1_2_3_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3237"},{"key":"e_1_2_3_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(16)30012-2"},{"key":"e_1_2_3_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3267"}],"container-title":["Diabetes\/Metabolism Research and Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdmrr.3249","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dmrr.3249","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dmrr.3249","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dmrr.3249","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T13:58:55Z","timestamp":1695909535000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dmrr.3249"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":24,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1002\/dmrr.3249"],"URL":"https:\/\/doi.org\/10.1002\/dmrr.3249","archive":["Portico"],"relation":{},"ISSN":["1520-7552","1520-7560"],"issn-type":[{"value":"1520-7552","type":"print"},{"value":"1520-7560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"2019-11-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e3249"}}