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The 10\u2010g monofilament and a foot exam are the commonly used methods for screening diabetic neuropathy, but this primarily identifies moderate to severe diabetic neuropathy. Small fibres are damaged early and are associated with the development of painful diabetic neuropathy, foot ulceration, and Charcot foot. Tests of small fibre damage include thermal thresholds, microneurography, evoked potentials, sudomotor function, laser Doppler flare, skin biopsy, and corneal confocal microscopy. Measures of small fibre damage and repair may be key to the assessment of efficacy in clinical trials of disease modifying therapies for diabetic neuropathy.<\/jats:p>","DOI":"10.1002\/dmrr.3255","type":"journal-article","created":{"date-parts":[[2019,12,12]],"date-time":"2019-12-12T04:38:38Z","timestamp":1576125518000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Diabetic neuropathy: A focus on small fibres"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7188-8903","authenticated-orcid":false,"given":"Rayaz A.","family":"Malik","sequence":"first","affiliation":[{"name":"Department of Medicine Weill\u2010Cornell Medicine\u2010Qatar  Doha Qatar"},{"name":"Division of Cardiovascular Sciences, School of Medical Sciences University of Manchester  Manchester 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