{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:35:06Z","timestamp":1783488906518,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,1,26]],"date-time":"2021-01-26T00:00:00Z","timestamp":1611619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Metabolism Res"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Diabetic ketoacidosis (DKA) is a known complication of patients with diabetes mellitus. The aim of this study was to compare the outcomes of patients admitted with a diagnosis of DKA with, and without, diastolic heart failure (DHF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a population\u2010based, retrospective, observational study using data from the National Inpatient Sample database for the years 2016 and 2017. The primary outcome was in\u2010hospital mortality. Secondary outcomes were rates of sepsis, non\u2010ST elevation myocardial infarctions (NSTEMI), acute kidney failure, acute respiratory failure (ARF), deep vein thrombosis, pulmonary embolism, mean length of hospital stay (LOS) and total hospital charges (THC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was no statistically significant difference for the adjusted odds for in\u2010hospital mortality between patients with and without DHF (adjusted odds ratio [aOR]: 0.55, 95% confidence interval [CI] 0.28\u20131.08,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.081). Patients with DKA and DHF had increased odds of developing an NSTEMI (aOR: 1.31, 95% CI: 1.01\u20131.70,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.045) or ARF (aOR: 1.82, 95% CI: 1.38\u20132.40,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) during the same admission compared to patients without DHF. Patients with DKA and DHF also had an increased mean THC (6500 CI: 1900\u201311,200,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.0006) in US dollars and increased LOS (0.7, 95% CI: 0.2\u20131.3,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.011) in days when compared to patients without DHF.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patients with DKA showed no statistically significant difference in mortality if they did or did not have a secondary diagnosis of DHF within the same admission.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dmrr.3435","type":"journal-article","created":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T10:09:37Z","timestamp":1610705377000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparing outcomes of diabetic ketoacidosis hospitalisations in patients with diastolic heart failure: A retrospective propensity matched analysis of the nationwide inpatient sample"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9456-4581","authenticated-orcid":false,"given":"Hafeez","family":"Shaka","sequence":"first","affiliation":[{"name":"John H. Stronger Jr. Hospital of Cook County  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zain","family":"El\u2010Amir","sequence":"additional","affiliation":[{"name":"College of Medicine Central Michigan University  Saginaw Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Aljadah","sequence":"additional","affiliation":[{"name":"Medical College of Wisconsin  Milwaukee Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farah","family":"Wani","sequence":"additional","affiliation":[{"name":"Samaritan Medical Center  Watertown New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genero","family":"Velazquez","sequence":"additional","affiliation":[{"name":"John H. Stronger Jr. Hospital of Cook County  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asim","family":"Kichloo","sequence":"additional","affiliation":[{"name":"College of Medicine Central Michigan University  Saginaw Michigan USA"},{"name":"Samaritan Medical Center  Watertown New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.5.1047"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pdi.1852"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2011.03246.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc4901.102568"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00381-9"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2003.10.021"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2003.11.002"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.hdx.0000080714.87750.48"},{"key":"e_1_2_9_10_1","volume-title":"Introduction to the HCUP National Inpatient Sample (NIS). The National (nationwide) Inpatient Sample Database Documentation","author":"Healthcare Cost and Utilization Project","year":"2017"},{"key":"e_1_2_9_11_1","volume-title":"HCUP NIS Related Reports","author":"Houchens R","year":"2014"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198307213090307"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0009922808323907"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.2337\/diaclin.22.4.198"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3408"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.728550"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anclin.2009.07.008"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2010.04.010"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvy038"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/62.3.275"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2017.04.012"}],"container-title":["Diabetes\/Metabolism Research and Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dmrr.3435","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dmrr.3435","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dmrr.3435","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T04:48:50Z","timestamp":1693198130000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dmrr.3435"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,26]]},"references-count":21,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1002\/dmrr.3435"],"URL":"https:\/\/doi.org\/10.1002\/dmrr.3435","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/DMRR.3435\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/DMRR.3435\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/DMRR.3435\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/DMRR.3435\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/DMRR.3435\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/DMRR.3435\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/DMRR.3435\/v1\/decision1","asserted-by":"object"}]},"ISSN":["1520-7552","1520-7560"],"issn-type":[{"value":"1520-7552","type":"print"},{"value":"1520-7560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,26]]},"assertion":[{"value":"2020-11-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e3435"}}