{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:15:09Z","timestamp":1792084509087,"version":"4.4.0"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T00:00:00Z","timestamp":1654646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001792","name":"James Cook University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001792","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003550","name":"Queensland Government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003550","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100016058","name":"Townsville Hospital and Health Service","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100016058","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Metabolism Res"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To perform an updated systematic review of randomised controlled trials examining the efficacy of at\u2010home foot temperature monitoring in reducing the risk of a diabetes\u2010related foot ulcer (DFU).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Systematic review performed according to Preferred Reporting Items for Systematic reviews and Meta\u2010Analyses guidelines. Risk\u2010of\u2010bias was assessed using version 2 of the Cochrane risk\u2010of\u2010bias tool. Meta\u2010analyses were performed using random effect models. Leave\u2010one\u2010out sensitivity analyses and a sub\u2010analysis excluding trials considered at high risk\u2010of\u2010bias assessed the consistency of the findings. The certainty of the evidence was assessed with GRADE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Five randomised controlled trials involving 772 participants meeting the International Working Group on the Diabetic Foot (IWGDF) risk category 2 or 3 were included. All trials reported instructing participants to measure skin temperature at\u2010home at six or more sites on each foot using a hand\u2010held infra\u2010red thermometer at least daily and reduce ambulatory activity in response to hotspots (temperature differences &gt;2.2\u00b0C on two consecutive days between similar locations in both feet). One, one, and three trials were considered at low, moderate and high risk\u2010of\u2010bias, respectively. Participants allocated to at\u2010home foot temperature monitoring had a reduced risk of developing a DFU (relative risk 0.51, 95% CI 0.31\u20130.84) compared to controls. Sensitivity and sub\u2010analyses suggested that the significance of this finding was consistent. The GRADE assessment suggested a low degree of certainty in the finding.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>At\u2010home daily foot temperature monitoring and reduction of ambulatory activity in response to hotspots reduce the risk of a DFU in moderate or high risk people with a low level of certainty.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dmrr.3549","type":"journal-article","created":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T20:23:30Z","timestamp":1653337410000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Efficacy of at home monitoring of foot temperature for risk reduction of diabetes\u2010related foot ulcer: A meta\u2010analysis"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5779-8848","authenticated-orcid":false,"given":"Jonathan","family":"Golledge","sequence":"first","affiliation":[{"name":"Ulcer and wound Healing consortium (UHEAL) Queensland Research Centre for Peripheral Vascular Disease College of Medicine and Dentistry James Cook University  Townsville Queensland Australia"},{"name":"Department of Vascular and Endovascular Surgery Townsville University Hospital  Townsville Queensland Australia"},{"name":"Australian Institute of Tropical Health and Medicine James Cook University  Townsville Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6108-893X","authenticated-orcid":false,"given":"Malindu E","family":"Fernando","sequence":"additional","affiliation":[{"name":"Ulcer and wound Healing consortium (UHEAL) Queensland Research Centre for Peripheral Vascular Disease College of Medicine and Dentistry James Cook University  Townsville Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanika","family":"Alahakoon","sequence":"additional","affiliation":[{"name":"Ulcer and wound Healing consortium (UHEAL) Queensland Research Centre for Peripheral Vascular Disease College of Medicine and Dentistry James Cook University  Townsville Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"Lazzarini","sequence":"additional","affiliation":[{"name":"School of Public Health and Social Work Queensland University of Technology  Brisbane Queensland Australia"},{"name":"Allied Health Research Collaborative Metro North Hospital and Health Service  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wouter B.","family":"aan de Stegge","sequence":"additional","affiliation":[{"name":"Amsterdam UMC, University of Amsterdam Department of Rehabilitation 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