{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T08:32:46Z","timestamp":1793694766148,"version":"4.5.1"},"reference-count":54,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T00:00:00Z","timestamp":1714435200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["837002508"],"award-info":[{"award-number":["837002508"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Metabolism Res"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Diabetes\u2010related foot ulcers are common, costly, and frequently recur. Multiple interventions help prevent these ulcers. However, none of these have been prospectively investigated for cost\u2010effectiveness. Our aim was to evaluate the cost\u2010effectiveness of at\u2010home skin temperature monitoring to help prevent diabetes\u2010related foot ulcer recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Multicenter randomized controlled trial. We randomized 304 persons at high diabetes\u2010related foot ulcer risk to either usual foot care plus daily at\u2010home foot skin temperature monitoring (intervention) or usual care alone (control). Primary outcome was cost\u2010effectiveness based on foot care costs and quality\u2010adjusted life years (QALY) during 18 months follow\u2010up. Foot care costs included costs for ulcer prevention (e.g., footwear, podiatry) and for ulcer treatment when required (e.g., consultation, hospitalisation, amputation). Incremental cost\u2010effectiveness ratios were calculated for intervention versus usual care using probabilistic sensitivity analysis for willingness\u2010to\u2010pay\/accept levels up to \u20ac100,000.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The intervention had a 45% probability of being cost\u2010effective at a willingness\u2010to\u2010accept of \u20ac50,000 per QALY lost. This resulted from (non\u2010significantly) lower foot care costs in the intervention group (\u20ac6067 vs. \u20ac7376;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.45) because of (significantly) fewer participants with ulcer recurrence(s) in 18\u00a0months (36% vs. 47%;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.045); however, QALYs were (non\u2010significantly) lower in the intervention group (1.09 vs. 1.12;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.35), especially in those without foot ulcer recurrence (1.09 vs. 1.17;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.10).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>At\u2010home skin temperature monitoring for diabetes\u2010related foot ulcer prevention compared with usual care is at best equally cost\u2010effective. The intervention resulted in cost\u2010savings due to preventing foot ulcer recurrence and related costs, but this came at the expense of QALY loss, potentially from self\u2010monitoring burdens.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dmrr.3805","type":"journal-article","created":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T07:23:21Z","timestamp":1714461801000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Cost\u2010effectiveness of temperature monitoring to help prevent foot ulcer recurrence in people with diabetes: A multicenter randomized controlled trial"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6420-6046","authenticated-orcid":false,"given":"Jaap J.","family":"Van Netten","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine Amsterdam UMC location University of Amsterdam  Amsterdam the Netherlands"},{"name":"Amsterdam Movement Sciences Program Rehabilitation  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wouter B.","family":"Aan De Stegge","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine Amsterdam UMC location University of Amsterdam  Amsterdam the Netherlands"},{"name":"Department of Surgery Hospital Group Twente  Almelo the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel G. 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