{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:39:22Z","timestamp":1787315962995,"version":"build-2736575974"},"reference-count":36,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:00:00Z","timestamp":1748822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:00:00Z","timestamp":1748822400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Metabolism Res"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study aimed to explore the relationship between PA domains, PA intensity, sedentary time, cardiometabolic factors, inflammatory markers, and risk of diabetic kidney disease (DKD) in adults. It also examined potential moderators of the relationship between PA and DKD including age, race and ethnicity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>This cross\u2010sectional study used data from the 2017\u20132018 National Health and Nutrition Examination Survey and included participants aged \u2265 18\u00a0years. The survey subjectively measured PA using the Global Physical Activity Questionnaire. After conducting multiple imputations to address missing data, we performed hierarchical logistic regression to identify factors significantly associated with DKD diagnosis and to examine moderating effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>DKD prevalence was 13.32%. Non\u2010Hispanic Black participants showed higher odds of DKD than non\u2010Hispanic White participants. Age, waist circumference, systolic blood pressure, fasting glucose levels, haemoglobin A1C, high\u2010sensitivity C\u2010reactive protein, sedentary time, and occupation\u2010related PA were significant predictors of DKD. Although age, race and ethnicity were significant predictors of DKD, we observed no moderating effects of these variables on the PA\u2010DKD risk relationship.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Cardiometabolic markers, inflammatory markers, and sedentary time significantly increase DKD risk, whereas occupation\u2010related PA serves as a protective factor. This study highlights the need for interventions promoting a more active lifestyle in diabetic populations to mitigate their DKD risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dmrr.70055","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T09:48:58Z","timestamp":1748857738000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Role of Physical Activity in Reducing Diabetic Kidney Disease Risk in Adults: Data From the National Health and Nutrition Examination Survey, 2017\u20132018"],"prefix":"10.1002","volume":"41","author":[{"given":"Wirampa","family":"Tanglai","sequence":"first","affiliation":[{"name":"Department of Biobehavioral Nursing Science College of Nursing University of Illinois Chicago  Chicago Illinois USA"},{"name":"Princess Agrarajakumari College of Nursing Chulabhorn Royal Academy  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apichai","family":"Wattanapisit","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine School of Medicine Walailak University  Nakhon Si Thammarat Thailand"},{"name":"Research Division Walailak University Hospital  Nakhon Si Thammarat Thailand"},{"name":"Excellence Center of Community Health Promotion Walailak University  Nakhon Si Thammarat Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Faculty of Medical Sciences Department of Physical Therapy Teikyo University of Science  Adachi City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanakrit","family":"Jeamjitvibool","sequence":"additional","affiliation":[{"name":"Department of Biobehavioral Nursing Science College of Nursing University of Illinois Chicago  Chicago Illinois USA"},{"name":"Princess Agrarajakumari College of Nursing Chulabhorn Royal Academy  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Lockwood","sequence":"additional","affiliation":[{"name":"Department of Biobehavioral Nursing Science College of Nursing University of Illinois Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2331-1229","authenticated-orcid":false,"given":"Mia","family":"Cajita","sequence":"additional","affiliation":[{"name":"Department of Biobehavioral Nursing Science College of Nursing University of Illinois Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2021.109119"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/kidneydial2030038"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2024.111729"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2017.181"},{"key":"e_1_2_9_6_1","first-page":"101","volume-title":"Sex and Gender Differences in Chronic Kidney Disease and Access to Care Around the Globe","author":"Garc\u00eda G. 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