{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T07:48:46Z","timestamp":1792136926462,"version":"4.4.0"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["101095556"],"award-info":[{"award-number":["101095556"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Metabolism Res"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To identify publications that describe RWD databases in the field of diabetes and map their key characteristics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Databases were searched (MEDLINE, SCOPUS, CINAHL from January 2018 to October 2025) to identify relevant publications describing RWD databases. Eligible studies were identified as RWD databases that contained more than 1000 adults and were followed up for one year or longer. Metadata including population, sample size, and outcomes were then extracted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 610 eligible RWD databases were identified from 1779 included articles. Databases were identified in 74 countries, with the majority collected in Europe (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0193). Only 22 databases were identified in lower\u2010 and\u2010 middle income countries (as defined by the World Bank). Demographics, prescription, diagnosis, and biochemical information were collected frequently; however, mortality and technology related variables (CGM usage) were found in fewer datasets. Very few databases were open access however 205 mentioned having the possibility for data sharing.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We have produced an online dashboard to summarise the RWD databases available in the field of diabetes. We found many RWD databases globally that contain a range of variables related to individuals' health; however, lower\u2010 and middle\u2010income nations are underrepresented within these data.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dmrr.70241","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T07:10:14Z","timestamp":1792134614000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Real\u2010World Databases in Diabetes: A Systematic Review"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9886-0169","authenticated-orcid":false,"given":"Jonah J.\u00a0C.","family":"Thomas","sequence":"first","affiliation":[{"name":"University of Leicester University Road  Leicester UK"},{"name":"Leicester Diabetes Centre Gwendolen Road  Leicester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9491-6110","authenticated-orcid":false,"given":"Anna","family":"Meffen","sequence":"additional","affiliation":[{"name":"University of Leicester University Road  Leicester UK"},{"name":"Leicester Diabetes Centre Gwendolen Road  Leicester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8309-4051","authenticated-orcid":false,"given":"Alessandro","family":"Rizzi","sequence":"additional","affiliation":[{"name":"University of Leicester University Road  Leicester UK"},{"name":"Leicester Diabetes Centre Gwendolen Road  Leicester UK"},{"name":"Diabetes Care Unit Universit\u00e0 Cattolica del Sacro Cuore Fondazione Policlinico Agostino Gemelli IRCCS  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew P.","family":"Kingsnorth","sequence":"additional","affiliation":[{"name":"School of Sport, Exercise and Health Sciences Loughborough University  Loughborough UK"},{"name":"NIHR Leicester Biomedical Research Centre  Leicester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7062-9811","authenticated-orcid":false,"given":"Beatrice","family":"Pieri","sequence":"additional","affiliation":[{"name":"University of Leicester University Road  Leicester UK"},{"name":"Leicester Diabetes Centre Gwendolen Road  Leicester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"He","sequence":"additional","affiliation":[{"name":"Department of Mathematics and Statistics University of Strathclyde  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9707-3816","authenticated-orcid":false,"given":"Shirley","family":"Konnor","sequence":"additional","affiliation":[{"name":"University of Leicester University Road  Leicester UK"},{"name":"Leicester Diabetes Centre Gwendolen Road  Leicester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8417-9700","authenticated-orcid":false,"given":"Clare","family":"Gillies","sequence":"additional","affiliation":[{"name":"University of Leicester University Road  Leicester UK"},{"name":"Leicester Diabetes Centre Gwendolen Road  Leicester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamlesh","family":"Khunti","sequence":"additional","affiliation":[{"name":"University of Leicester University Road  Leicester UK"},{"name":"Leicester Diabetes Centre Gwendolen Road  Leicester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9756-4061","authenticated-orcid":false,"given":"Jonathan","family":"Valabhji","sequence":"additional","affiliation":[{"name":"Department of Metabolism, Digestion &amp; Reproduction Faculty of Medicine, Imperial  London UK"},{"name":"Department of Diabetes and Endocrinology Chelsea and Westminster Hospital NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivani","family":"Misra","sequence":"additional","affiliation":[{"name":"Department of Metabolism, Digestion &amp; Reproduction Faculty of Medicine, Imperial  London UK"},{"name":"Department of Diabetes &amp; Endocrinology Imperial College Healthcare NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Adler","sequence":"additional","affiliation":[{"name":"Diabetes Trials Unit Radcliffe Department of Medicine University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Torp\u2010Pedersen","sequence":"additional","affiliation":[{"name":"Copenhagen University Hospital Steno Diabetes Center Copenhagen  Herlev Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5020-1818","authenticated-orcid":false,"given":"Martina","family":"Vettoretti","sequence":"additional","affiliation":[{"name":"Department of Information Engineering University of Padova  Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7854-4233","authenticated-orcid":false,"given":"Julia K.","family":"Mader","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Diabetology Department of Internal Medicine Medical University of Graz  Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratik","family":"Choudhary","sequence":"additional","affiliation":[{"name":"University of Leicester University Road  Leicester UK"},{"name":"Leicester Diabetes Centre Gwendolen Road  Leicester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,16]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cpt.857"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.316.7126.201"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12874\u2010022\u201001768\u20106"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2015.09.2938"},{"key":"e_1_2_11_6_1","unstructured":"Administration USFaD \u201cReal\u2010World Evidence 2024 \u201d (2024) https:\/\/www.fda.gov\/science\u2010research\/science\u2010and\u2010research\u2010special\u2010topics\/real\u2010world\u2010evidence."},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmsb1609216"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13929"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125\u2010020\u201005174\u20109"},{"key":"e_1_2_11_10_1","unstructured":"Diabetes RWDfDi \u201cREDDIE \u201d (2024) https:\/\/www.reddie\u2010diabetes.eu\/."},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.117.029190"},{"key":"e_1_2_11_12_1","unstructured":"ONCOVALUE \u201cONCOVALUE \u201d (2024) https:\/\/oncovalue.org\/."},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00592\u2010020\u201001576\u20108"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.7189\/jogh.11.04040"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/02255189.2014.876390"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2022.05.019"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889\u2010022\u201014213\u20106"}],"container-title":["Diabetes\/Metabolism Research and Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dmrr.70241","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dmrr.70241","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dmrr.70241","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T07:10:16Z","timestamp":1792134616000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dmrr.70241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1002\/dmrr.70241"],"URL":"https:\/\/doi.org\/10.1002\/dmrr.70241","archive":["Portico"],"relation":{},"ISSN":["1520-7552","1520-7560"],"issn-type":[{"value":"1520-7552","type":"print"},{"value":"1520-7560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"2026-06-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70241"}}