{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T03:47:45Z","timestamp":1774410465365,"version":"3.50.1"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,12,22]],"date-time":"2006-12-22T00:00:00Z","timestamp":1166745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Developmental Neurobiology"],"published-print":{"date-parts":[[2007,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Concepts on neuronal signal processing and integration at a cellular and subcellular level are driven by recording techniques and model systems available. The cricket CNS with the omega\u20101\u2010neurone (ON1) provides a model system for auditory pattern recognition and directional processing. Exploiting ON1's planar structure we simultaneously imaged free intracellular Ca<jats:sup>2+<\/jats:sup> at both input and output neurites and recorded the membrane potential <jats:italic>in vivo<\/jats:italic> during acoustic stimulation. In response to a single sound pulse the rate of Ca<jats:sup>2+<\/jats:sup> rise followed the onset spike rate of ON1, while the final Ca<jats:sup>2+<\/jats:sup> level depended on the mean spike rate. Ca<jats:sup>2+<\/jats:sup> rapidly increased in both dendritic and axonal arborizations and only gradually in the axon and the cell body. Ca<jats:sup>2+<\/jats:sup> levels were particularly high at the spike\u2010generating zone. Through the activation of a Ca<jats:sup>2+<\/jats:sup>\u2010sensitive K<jats:sup>+<\/jats:sup> current this may exhibit a specific control over the cell's electrical response properties. In all cellular compartments presentation of species\u2010specific calling song caused distinct oscillations of the Ca<jats:sup>2+<\/jats:sup> level in the chirp rhythm, but not the faster syllable rhythm. The Ca<jats:sup>2+<\/jats:sup>\u2010mediated hyperpolarization of ON1 suppressed background spike activity between chirps, acting as a noise filter. During directional auditory processing, the functional interaction of Ca<jats:sup>2+<\/jats:sup>\u2010mediated inhibition and contralateral synaptic inhibition was demonstrated. Upon stimulation with different sound frequencies, the dendrites, but not the axonal arborizations, demonstrated a tonotopic response profile. This mirrored the dominance of the species\u2010specific carrier frequency and resulted in spatial filtering of high frequency auditory inputs. \u00a9 2006 Wiley Periodicals, Inc. J Neurobiol 67: 68\u201380, 2007<\/jats:p>","DOI":"10.1002\/dneu.20323","type":"journal-article","created":{"date-parts":[[2006,12,22]],"date-time":"2006-12-22T19:51:40Z","timestamp":1166817100000},"page":"68-80","source":"Crossref","is-referenced-by-count":15,"title":["Neurite\u2010specific Ca<sup>2+<\/sup> dynamics underlying sound processing in an auditory 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