{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:00:31Z","timestamp":1762866031326,"version":"build-2065373602"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,10,5]],"date-time":"2012-10-05T00:00:00Z","timestamp":1349395200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Drug Testing and Analysis"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:p>5\u2010(2\u2010Aminopropyl)indole (5\u2010IT) and 3\u2010(2\u2010aminopropyl)indole (\u03b1\u2010methyltryptamine, AMT) are isomeric substances and their differentiation can be a challenge under routine analytical conditions, especially when reference material is unavailable. 5\u2010IT represents a very recent addition to the battery of new psychoactive substances that are commercially available from online retailers. This report illustrates how subtle differences observed under mass spectral and UV conditions can help to facilitate the differentiation between the two isomers. Analyses included <jats:sup>1<\/jats:sup>\u2009H and <jats:sup>13<\/jats:sup>C NMR, GC\u2010EI\/CI ion trap MS, applications of several U\/HPLC\u2010DAD and HPLC\u2010MS methods. Investigations currently underway also highlight the confirmation that AMT was detected in a number of fatal intoxications. These findings also demonstrate that there is a potential risk of misidentification when dealing with both substances. Copyright \u00a9 2012 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/dta.1420","type":"journal-article","created":{"date-parts":[[2012,10,5]],"date-time":"2012-10-05T14:04:47Z","timestamp":1349445887000},"page":"196-202","source":"Crossref","is-referenced-by-count":31,"title":["AMT (3\u2010(2\u2010aminopropyl)indole) and 5\u2010IT (5\u2010(2\u2010aminopropyl)indole): an analytical challenge and implications for forensic analysis"],"prefix":"10.1002","volume":"5","author":[{"given":"Simon P.","family":"Elliott","sequence":"first","affiliation":[{"name":"ROAR Forensics  Malvern Hills Science Park, Geraldine Road, Malvern WR14 3SZ UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon D.","family":"Brandt","sequence":"additional","affiliation":[{"name":"School of Pharmacy and Biomolecular Sciences Liverpool John Moores University  Byrom Street Liverpool L3 3AF UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sally","family":"Freeman","sequence":"additional","affiliation":[{"name":"School of Pharmacy and Pharmaceutical Sciences The University of Manchester  Oxford Road Manchester M13 9PT UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland P.","family":"Archer","sequence":"additional","affiliation":[{"name":"States Analyst's Laboratory, Longue Rue  St Martin's GY4 6LD Guernsey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,10,5]]},"reference":[{"volume-title":"TIHKAL: The Continuation","year":"1997","author":"Shulgin A.T.","key":"e_1_2_6_2_1"},{"key":"e_1_2_6_3_1","unstructured":"A.Hofmann F.Troxler.Nouveaux d\u00e9riv\u00e9s de l'indole et leur pr\u00e9paration French Patent No. 1344579 1963."},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hlca.19680510717"},{"key":"e_1_2_6_5_1","unstructured":"EMCDDA\/Europol.EMCDDA\u2013Europol 2011 Annual Report on the Implementation of Council Decision 2005\/387\/JHA. 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