{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:45:33Z","timestamp":1791297933104,"version":"4.1.0"},"reference-count":11,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2014,5,9]],"date-time":"2014-05-09T00:00:00Z","timestamp":1399593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Drug Testing and Analysis"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:p>Hair analysis of ethyl glucuronide (EtG) has become a valuable marker for the detection of moderate and chronic alcohol consumption. It has been shown that bleaching and perming may decrease EtG content in hair. So far, no studies exist about the influence of thermal hair straightening on EtG content in hair.<\/jats:p><jats:p>Forty\u2010one positive EtG hair samples were treated <jats:italic>in vitro<\/jats:italic> with a hair straightener at 200\u00b0C. Duration of treatment of 1 min was chosen for this study. After washing, pulverization, incubation in ultrasonic bath, solid\u2010phase extraction, and derivatization with heptafluorobutyric anhydride, EtG was determined by gas chromatography\u2010mass spectrometry \u2013 negative ion chemical ionization (GC\u2010MS\u2010NICI). The EtG contents in straightened hair strands were then compared with those in the corresponding untreated strands. In 20 of 41 hair samples, a decrease of EtG content was found ranging from 0.7% to 79.3% (average 20%) whereas in 21 cases an increase was shown ranging from 2.0% to 50.9% (average 15%). The variation of the results seems to depend on hair colour. The decrease may be explained by thermic <jats:italic>in vitro<\/jats:italic> destruction of EtG. The increase may be explained by denaturation of the hair matrix by thermal treatment possibly causing a better extraction of EtG during incubation in ultrasonic bath. This <jats:italic>in vitro study<\/jats:italic> indicates that thermal hair straightening has an impact on the EtG content in hair. This has to be considered for a correct interpretation of EtG results in hair. However, these results should be confirmed by <jats:italic>in vivo<\/jats:italic> studies. Copyright \u00a9 2014 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/dta.1648","type":"journal-article","created":{"date-parts":[[2014,5,9]],"date-time":"2014-05-09T08:42:49Z","timestamp":1399624969000},"page":"74-77","source":"Crossref","is-referenced-by-count":42,"title":["Influence of thermal hair straightening on ethyl glucuronide content in hair"],"prefix":"10.1002","volume":"6","author":[{"given":"Jana","family":"Ettlinger","sequence":"first","affiliation":[{"name":"Laboratoire National de Sant\u00e9 Division de Toxicology  L\u20101511 Luxembourg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Kirchen","sequence":"additional","affiliation":[{"name":"Laboratoire National de Sant\u00e9 Division de Toxicology  L\u20101511 Luxembourg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Yegles","sequence":"additional","affiliation":[{"name":"Laboratoire National de Sant\u00e9 Division de Toxicology  L\u20101511 Luxembourg"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,5,9]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/FTD.0b013e318167d602"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1051\/ata:2005011"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2004.04.032"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2009.11.005"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2011.10.006"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/FTD.0b013e31828ca246"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-011-4685-0"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2011.10.015"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2011.10.009"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2013.05.010"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0142-5463.2004.00223_2.x"}],"container-title":["Drug Testing and Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdta.1648","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dta.1648","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T20:26:59Z","timestamp":1760387219000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/dta.1648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,9]]},"references-count":11,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1002\/dta.1648"],"URL":"https:\/\/doi.org\/10.1002\/dta.1648","archive":["Portico"],"relation":{},"ISSN":["1942-7603","1942-7611"],"issn-type":[{"value":"1942-7603","type":"print"},{"value":"1942-7611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,9]]}}}