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Development of markers of exposure to CWA is necessary to distinguish exposed victims from unexposed ones. We present the first study of hair usage as passive sampler to assess contamination by chemicals in vapour form. This work presents more particularly the hair adsorption capacity for methyl salicylate used as a surrogate of the vesicant sulphur mustard. Chemical vapours toxicity through the respiratory route has historically been defined through Haber's law's concentration\u2010time (Ct) product, and vapour exposure of hair to methyl salicylate was conducted with various times or doses of exposure in the range of incapacitating and lethal Ct products corresponding to sulphur mustard. Following exposure, extraction of methyl salicylate from hair was conducted by simple soaking in dichloromethane. Methyl salicylate could be detected on hair for vapour concentration corresponding to about one fifth of the sulphur mustard concentration that would kill 50% of exposed individuals (LCt50). The amount of methyl salicylate recovered from hair increased with time or dose of exposure. It showed a good correlation with the concentration\u2010time product, suggesting that hair could be used like a passive sampler to assess vapour exposure to chemical compounds. It introduces great perspectives concerning the use of hair as a marker of exposure to CWA. Copyright \u00a9 2014 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/dta.1659","type":"journal-article","created":{"date-parts":[[2014,5,9]],"date-time":"2014-05-09T08:42:49Z","timestamp":1399624969000},"page":"67-73","source":"Crossref","is-referenced-by-count":24,"title":["Hair analysis as a useful procedure for detection of vapour exposure to chemical warfare agents: simulation of sulphur mustard with methyl salicylate"],"prefix":"10.1002","volume":"6","author":[{"given":"Marie","family":"Spiandore","sequence":"first","affiliation":[{"name":"Aix Marseille Universi\u00e9  CNRS, LCE FRE 3416 13331 Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Piram","sequence":"additional","affiliation":[{"name":"Aix Marseille Universi\u00e9  CNRS, LCE FRE 3416 13331 Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Lacoste","sequence":"additional","affiliation":[{"name":"Bataillon des Marins Pompiers de Marseille, BMPM  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Josse","sequence":"additional","affiliation":[{"name":"Service D\u00e9partemental d'Incendie et de Secours des Alpes\u2010Maritimes  SDIS06 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Doumenq","sequence":"additional","affiliation":[{"name":"Aix Marseille Universi\u00e9  CNRS, LCE FRE 3416 13331 Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,5,9]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"NATO Handbook on the Medical Aspects of NBC Defensive Operations AMedP\u20106(B). 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