{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:28:49Z","timestamp":1760401729736,"version":"build-2065373602"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,11,27]],"date-time":"2021-11-27T00:00:00Z","timestamp":1637971200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug Testing and Analysis"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Drug Enforcement Administration's (DEA) Cocaine Signature Program previously identified 19 coca\u2010growing regions within South America and developed methodology to geo\u2010source cocaine using a combination of trace cocaine alkaloids, stable isotopes, and multivariate statistics. Twenty\u2010nine coca leaf samples collected in 2016 and 2019 from a previously unanalyzed coca\u2010growing region located in Puno, Peru, were analyzed with this methodology. Trace cocaine alkaloids and stable isotopes were compared with other Peruvian regions. Minor differences were observed in the extracted cocaine alkaloid profiles when compared with samples collected from the Ucayali\u2010Huallaga Valley and Cusco\u2010Apurimac regions while the stable isotopes of \u03b4<jats:sup>2<\/jats:sup>H (\u2212177.1\u2030) and \u03b4<jats:sup>18<\/jats:sup>O (23.8\u2030) were enriched. Puno's alkaloid and stable isotope results are presented in this publication to assist forensic laboratories and enhance their cocaine geo\u2010sourcing capabilities.<\/jats:p>","DOI":"10.1002\/dta.3198","type":"journal-article","created":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T21:08:54Z","timestamp":1636664934000},"page":"519-524","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Advances in cocaine signature methodology: Alkaloid and isotope profiles of coca grown in Puno, Peru"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1320-8543","authenticated-orcid":false,"given":"Laura M.","family":"Jones","sequence":"first","affiliation":[{"name":"Special Testing and Research Laboratory US Drug Enforcement Administration  Dulles Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2506-0750","authenticated-orcid":false,"given":"Kristin E.","family":"Ceniccola\u2010Campos","sequence":"additional","affiliation":[{"name":"Special Testing and Research Laboratory US Drug Enforcement Administration  Dulles Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0325-0278","authenticated-orcid":false,"given":"David R.","family":"Morello","sequence":"additional","affiliation":[{"name":"Special Testing and Research Laboratory US Drug Enforcement Administration  Dulles Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,11,27]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Drug Enforcement Administration (DEA).National drug threat assessment.2020https:\/\/www.dea.gov\/documents\/2021\/03\/02\/2020-national-drug-threat-assessment. Accessed April 9 2021."},{"key":"e_1_2_6_3_1","unstructured":"European Union (EU).Drug markets report 2019.https:\/\/www.emcdda.europa.eu\/publications\/joint-publications\/eu-drug-markets-report-2019_en. Accessed April 9 2021."},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/35042680"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep23520"},{"key":"e_1_2_6_6_1","unstructured":"Office of National Drug Control Policy.ONDCP releases data on coca cultivation and production in Peru. White House press release July 31 2020.https:\/\/trumpwhitehouse.archives.gov\/briefings\u2010statements\/ondcp\u2010releases\u2010data\u2010coca\u2010cultivation\u2010production\u2010peru\u2010073120\/. 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