{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T13:22:49Z","timestamp":1789132969081,"version":"build-2803163510"},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,1,17]],"date-time":"2022-01-17T00:00:00Z","timestamp":1642377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug Testing and Analysis"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Since rodenticides represent a substance group relevant in toxicological analyses, the aim of this work was the development of a complex multi\u2010target screening strategy for the identification with liquid chromatography\u2013tandem mass spectrometry. A simple protein precipitation was used as the sample preparation strategy. Further, a Luna 5\u00a0\u03bcm C18 (2) 100\u2009\u00c5, 150\u2009\u00d7\u00a02\u00a0mm analytical column was applied for the separation of relevant analytes with a Shimadzu HPLC. Signal detection was performed with a SCIEX API 5500 QTrap MS\/MS system. The rodenticides investigated (\u03b1\u2010chloralose, brodifacoum, bromadiolone, coumatetralyl, difenacoum, and warfarin) could be incorporated effectively into a multi\u2010target screening strategy covering about 250 substances representing different groups with a limit of detection appropriate for substance identification. The strategy can easily be modified to perform semi\u2010quantitative measurements for this substance group and could be supplemented by quantification based on standard addition.<\/jats:p>","DOI":"10.1002\/dta.3222","type":"journal-article","created":{"date-parts":[[2022,1,8]],"date-time":"2022-01-08T01:26:09Z","timestamp":1641605169000},"page":"1149-1154","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Antemortem and postmortem rodenticide analysis in forensic toxicology as a part of an LC\u2010MS\/MS\u2010based multi\u2010target screening strategy"],"prefix":"10.1002","volume":"14","author":[{"given":"Annabel","family":"Arens","sequence":"first","affiliation":[{"name":"Institute of Legal Medicine Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Teske","sequence":"additional","affiliation":[{"name":"Institute of Legal Medicine Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Klintschar","sequence":"additional","affiliation":[{"name":"Institute of Legal Medicine Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reinhard","family":"Mischke","sequence":"additional","affiliation":[{"name":"Small Animal Clinic University of Veterinary Medicine Hannover, Foundation  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6748-296X","authenticated-orcid":false,"given":"Marek","family":"Dziadosz","sequence":"additional","affiliation":[{"name":"Institute of Legal Medicine Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,1,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/15563650.2017.1388087"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.5070\/V420110128"},{"key":"e_1_2_6_4_1","first-page":"128","volume-title":"XV. 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