{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T12:28:56Z","timestamp":1789907336964,"version":"4.0.1"},"reference-count":37,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T00:00:00Z","timestamp":1671408000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug Testing and Analysis"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Decades of research show that constituents other than nicotine are the harmful agents in tobacco products. This knowledge is incorporated into the nicotine regulatory policies of countries leading in tobacco control, such as the UK and New Zealand. Alternative nicotine products, such as nicotine replacement therapy and e\u2010cigarettes, are now endorsed in the UK by a number of healthcare bodies in a tobacco harm reduction approach that encourages tobacco users to completely switch to a less risky nicotine\u2010containing product. The potential role of \u2018clean\u2019 nicotine alternatives to reduce the harms from tobacco is, however, not being translated into practice. Many healthcare practitioners still bundle tobacco, cigarettes, smoking, cancer and nicotine into one, thus preventing them from supporting their patients to make informed choices on safer nicotine alternatives. This misperception among healthcare professionals, in turn, is a hurdle to effective tobacco control policymaking in many low\u2010 and middle\u2010income countries and effective cessation support everywhere in the world. Nicotine confidence based on nicotine literacy among the key decision\u2010makers should start with reforming medical curricula and myth\u2010busting in the lay media to include factual statements about nicotine and public health policy discussions on the principles of harm reduction.<\/jats:p>","DOI":"10.1002\/dta.3413","type":"journal-article","created":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T12:53:26Z","timestamp":1669121606000},"page":"1205-1210","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Confidence in nicotine for tobacco harm reduction\u2014Bridging the policy\u2013practice gap"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5670-6393","authenticated-orcid":false,"given":"Sudhanshu","family":"Patwardhan","sequence":"first","affiliation":[{"name":"Centre for Health Research and Education University of Southampton Science Park  Hampshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4682.739"},{"key":"e_1_2_9_3_1","volume-title":"Smoking and health (1962)","author":"Royal College of Physicians","year":"1962"},{"key":"e_1_2_9_4_1","volume-title":"Smoking and health: Report of the advisory committee to the surgeon general of the public health service","author":"US Public Health Service","year":"1964"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.309.6959.901"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.309.6959.937"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100714.1999.tb01985.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/mutage\/geh036"},{"key":"e_1_2_9_9_1","volume-title":"Guidelines for implementation of article 14","author":"WHO Framework Convention on Tobacco Control","year":"2013"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/tobaccocontrol\u20102018\u2010054389"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1744\u20108603\u20106\u201022"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1108\/DAT\u201001\u20102020\u20100001"},{"key":"e_1_2_9_13_1","volume-title":"WHO report on the global tobacco epidemic 2019: Offer help to quit tobacco use","author":"World Health Organization","year":"2019"},{"key":"e_1_2_9_14_1","volume-title":"Smoking cessation. 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