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The two most prominent cannabinoids are delta\u20109\u2010tetrahydrocannabinol (\u0394<jats:sup>9<\/jats:sup>THC) and cannabidiol (CBD). Cannabis potency is measured not only by the \u0394<jats:sup>9<\/jats:sup>THC levels but also by the ratio of \u0394<jats:sup>9<\/jats:sup>THC to other non\u2010psychoactive cannabinoids, namely, CBD. Cannabis use was decriminalized in Jamaica in 2015, which opened the gates for the creation of a regulated medical cannabis industry in the country. To date, there is no information available on the potency of cannabis in Jamaica. In this study, the cannabinoid content of Jamaican\u2010grown cannabis was examined over the period 2014\u20132020. Two hundred ninety\u2010nine herbal cannabis samples were received from 12 parishes across the island, and the levels of the major cannabinoids were determined using gas chromatography\u2013mass spectrometry. There was a significant increase (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) in the median total THC levels of cannabis samples tested between 2014 (1.1%) and 2020 (10.2%). The highest median THC was detected in the central parish of Manchester (21.1%). During the period, THC\/CBD ratios increased from 2.1 (2014) to 194.1 (2020), and there was a corresponding increase in the percent freshness of samples (CBN\/THC ratios &lt;0.013). The data show that a significant increase in the potency of locally grown cannabis has occurred in Jamaica during the last decade.<\/jats:p>","DOI":"10.1002\/dta.3527","type":"journal-article","created":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T00:22:07Z","timestamp":1686615727000},"page":"174-186","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Potency trends of cannabis in Jamaica during the period of 2014 to 2020"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4216-7186","authenticated-orcid":false,"given":"Carole M.","family":"Lindsay","sequence":"first","affiliation":[{"name":"Department of Basic Medical Sciences, Faculty of Medical Sciences The University of the West Indies (UWI)  Kingston Jamaica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalia K.","family":"Bernard","sequence":"additional","affiliation":[{"name":"Department of Basic Medical Sciences, Faculty of Medical Sciences The University of the West Indies (UWI)  Kingston Jamaica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda M.","family":"Hammond","sequence":"additional","affiliation":[{"name":"Department of Basic Medical Sciences, Faculty of Medical Sciences The University of the West Indies (UWI)  Kingston Jamaica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheldon","family":"Beckford","sequence":"additional","affiliation":[{"name":"Department of Basic Medical Sciences, Faculty of Medical Sciences The University of the West Indies (UWI)  Kingston Jamaica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendel D.","family":"Abel","sequence":"additional","affiliation":[{"name":"Department of Community Health and Psychiatry, Faculty of Medical Sciences The University of the West Indies (UWI)  Kingston Jamaica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul D.","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Basic Medical Sciences, Faculty of Medical Sciences The University of the West Indies (UWI)  Kingston Jamaica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauriann E.","family":"Young","sequence":"additional","affiliation":[{"name":"Department of Basic Medical Sciences, Faculty of Medical Sciences The University of the West Indies (UWI)  Kingston Jamaica"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,6,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2005.09.011"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1039\/c6np00074f"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.175.4023.778"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042\u20107158.1972.tb08857.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20103\u20107091\u20108164\u20105_6"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1470919"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/42015"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plipres.2006.03.003"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/346561a0"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/365061a0"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0707442"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg143"},{"volume-title":"Marijuana and Medicine: Assessing the Science Base","year":"1999","author":"Benson JA","key":"e_1_2_8_14_1"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12631"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780199662685.003.0006"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780199662685.003.0007"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1124\/pr.110.003004"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2023.01.018"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2015.04.007"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-008045382-8.00091-5"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2005.09.014"},{"key":"e_1_2_8_23_1","unstructured":"BennettP.What influences degradation of THC and other cannabinoids? 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