{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:08:20Z","timestamp":1771459700606,"version":"3.50.1"},"reference-count":48,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T00:00:00Z","timestamp":1743984000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug Testing and Analysis"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>In collaboration with various Anti\u2010Doping Organisations and the Paris WADA\u2010accredited laboratory, the International Testing Agency spearheaded the implementation of the Endocrine Module ahead of the Olympic Games Paris 2024. This article presents a data\u2010driven evaluation of its early integration within Athlete Biological Passport (ABP) programs. The assessment of endocrine profile testing follows the complete ABP sample lifecycle, from collection to the submission of reports by the Athlete Passport Management Unit. The article identifies both challenges and opportunities by integrating testing, analytical and ABP perspectives and offers recommendations for the future development of the Endocrine Module. Furthermore, it explores the Endocrine Module's synergy with the Haematological and Steroidal Modules emphasising on key areas for the enhancement of ABP programs as a whole.<\/jats:p>","DOI":"10.1002\/dta.3892","type":"journal-article","created":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T04:36:58Z","timestamp":1744087018000},"page":"1865-1876","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluating the Early Operational Performance of the Endocrine Module in the Athlete Biological Passport"],"prefix":"10.1002","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4777-9130","authenticated-orcid":false,"given":"Miguel","family":"de\u00a0Figueiredo","sequence":"first","affiliation":[{"name":"International Testing Agency  Lausanne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2670-6939","authenticated-orcid":false,"given":"Alexandre","family":"Marchand","sequence":"additional","affiliation":[{"name":"Laboratoire AntiDopage Fran\u00e7ais (LADF)  Orsay France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3732-3105","authenticated-orcid":false,"given":"Damien","family":"Rhumorbarbe","sequence":"additional","affiliation":[{"name":"International Testing Agency  Lausanne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Mann","sequence":"additional","affiliation":[{"name":"International Testing Agency  Lausanne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0744-550X","authenticated-orcid":false,"given":"Jonas","family":"Saugy","sequence":"additional","affiliation":[{"name":"International Skating Union  Lausanne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1715-7587","authenticated-orcid":false,"given":"Neil","family":"Robinson","sequence":"additional","affiliation":[{"name":"International Testing Agency  Lausanne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1517-0777","authenticated-orcid":false,"given":"Louisa\u00a0M.","family":"Lobigs","sequence":"additional","affiliation":[{"name":"International Testing Agency  Lausanne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4123-3084","authenticated-orcid":false,"given":"Magnus","family":"Ericsson","sequence":"additional","affiliation":[{"name":"Laboratoire AntiDopage Fran\u00e7ais (LADF)  Orsay France"},{"name":"World Anti\u2010Doping Agency, Endocrine Working Group  Montreal Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1941738118782688"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003\u20104819\u2010148\u201010\u2010200805200\u201000215"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgae897"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228\u2010014\u20101743\u20105"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.59"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2006.027573"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjp.2008.99"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.3329"},{"key":"e_1_2_9_10_1","unstructured":"World Anti\u2010Doping Agency \u20182022 Anti\u2010Doping Testing Figures \u2019 Published online April (2024) https:\/\/www.wada\u2010ama.org\/sites\/default\/files\/2024\u201004\/2022_anti\u2010doping_testing_figures_en.pdf."},{"key":"e_1_2_9_11_1","unstructured":"World Anti\u2010Doping Agency \u201cWADA Technical Document \u2010 TD2021GH \u2010 Human Growth Hormone (Hgh) Isoform Differential Immunoassays for Doping Control Analyses \u201d Published online (2021) accessed September 26 2023 https:\/\/www.wada\u2010ama.org\/sites\/default\/files\/2022\u201001\/td2021gh_final_eng_0.pdf."},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.4.7379"},{"key":"e_1_2_9_13_1","unstructured":"World Anti\u2010Doping Agency \u2018Laboratory Guidelines \u2010 Human Growth Hormone (hGH) Biomarkers Test \u2010 Version 3.0 \u2019 Published Online (2021) accessed September 26 2023 https:\/\/www.wada\u2010ama.org\/sites\/default\/files\/resources\/files\/wada_guidelines_hgh_biomarkers_test_v3_jan_2021_eng.pdf."},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.2953"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2008.112458"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.2674"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.1787"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.2506"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/lpr\/mgm042"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgab799"},{"key":"e_1_2_9_21_1","unstructured":"World Anti\u2010Doping Agency \u2018Laboratory Guidelines \u2010 Analytical Requirements for the Endocrine Module of the Athlete Biological Passport \u2010 Version 1.0 \u2019 Published Online (2023) accessed September 26 2023 https:\/\/www.wada\u2010ama.org\/sites\/default\/files\/2023\u201007\/2023_laboratory_guidelines_endocrine_module_final_v1_0.pdf."},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004\u20100386"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ghir.2007.01.011"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002\u2010020037"},{"key":"e_1_2_9_25_1","unstructured":"World Anti\u2010Doping Agency \u2018Athlete Biological Passport Operating Guidelines \u2010 Version 9.0 \u2019 Published Online (2023) accessed September 26 2023 https:\/\/www.wada\u2010ama.org\/sites\/default\/files\/2023\u201007\/guidelines_abp_v9_2023_final_eng_1.pdf."},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.1666"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ghir.2013.03.006"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006\u20100612"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102265.2008.03319.x"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/cen.12445"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007\u20102801"},{"key":"e_1_2_9_32_1","unstructured":"World Anti\u2010Doping Agency \u2018World Anti\u2010Doping Code \u2019 Published Online (2021) accessed January 6 2025 https:\/\/www.wada\u2010ama.org\/sites\/default\/files\/resources\/files\/2021_wada_code.pdf."},{"key":"e_1_2_9_33_1","unstructured":"World Anti\u2010Doping Agency \u2018International Standard for the Protection of Privacy and Personal \u2019 Published Online (2021) accessed January 6 2025 https:\/\/www.wada\u2010ama.org\/sites\/default\/files\/2022\u201001\/international_standard_ispppi_\u2010_november_2021_0.pdf."},{"key":"e_1_2_9_34_1","unstructured":"World Anti\u2010Doping Agency \u2018International Standard for Testing and Investigations \u2019 Published Online (2023) accessed September 27 2023 https:\/\/www.wada\u2010ama.org\/sites\/default\/files\/2022\u201012\/isti_2023_w_annex_k_final_clean.pdf."},{"key":"e_1_2_9_35_1","unstructured":"World Anti\u2010Doping Agency \u2018International Standard for Laboratories \u2019 Published Online (2021) accessed November 26 2024 https:\/\/www.wada\u2010ama.org\/sites\/default\/files\/resources\/files\/isl_2021.pdf."},{"key":"e_1_2_9_36_1","unstructured":"World Anti Doping Agency \u2018WADA Technical Document for Sport Specific Analysis \u2019 Published Online (2023) accessed September 26 2023 https:\/\/www.wada\u2010ama.org\/sites\/default\/files\/2023\u201012\/tdssa_v9.0_clean_final.pdf."},{"key":"e_1_2_9_37_1","unstructured":"World Anti\u2010Doping Agency \u2018Guidelines for Sample Collection \u2019 Published online (2021) accessed November 25 2024 https:\/\/www.wada\u2010ama.org\/sites\/default\/files\/resources\/files\/isti_sample_collection_guidelines_en_final_2_feb_2021_0.pdf."},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.12557"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/hvaa043"},{"key":"e_1_2_9_40_1","unstructured":"World Anti\u2010Doping Agency \u201cWADA Technical Document \u2010 TD2023APMU \u2010 Athlete Passport Management Unit Requirements and Procedures \u201d Published Online (2023) accessed March 18 2025 https:\/\/www.wada\u2010ama.org\/sites\/default\/files\/2022\u201011\/td2023apmu_eng_final.pdf."},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.3343\/lmo.2017.7.2.66"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.3814"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.8066"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102265.1997.2111036.x"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2008.05.037"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.84.10.6037"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.85.1.6262"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpendmet0644"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ghir.2014.06.001"}],"container-title":["Drug Testing and Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dta.3892","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T16:28:13Z","timestamp":1767025693000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/dta.3892"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,7]]},"references-count":48,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/dta.3892"],"URL":"https:\/\/doi.org\/10.1002\/dta.3892","archive":["Portico"],"relation":{},"ISSN":["1942-7603","1942-7611"],"issn-type":[{"value":"1942-7603","type":"print"},{"value":"1942-7611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,7]]},"assertion":[{"value":"2025-02-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}