{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T04:46:31Z","timestamp":1788669991721,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T00:00:00Z","timestamp":1775347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T00:00:00Z","timestamp":1775347200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003569","name":"Ministry of Food and Drug Safety","doi-asserted-by":"publisher","award":["24211MFDS244"],"award-info":[{"award-number":["24211MFDS244"]}],"id":[{"id":"10.13039\/501100003569","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug Testing and Analysis"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The manufacture and distribution of illicit drugs in the Republic of Korea are an increasing problem. We aimed to develop a rapid and reliable simultaneous analytical method for monitoring the illegal presence of anabolic androgenic steroids (AAS) in foods and drugs. Forty\u2010five AAS compounds were analyzed using a validated liquid chromatography\u2013tandem mass spectrometry (LC\u2013MS\/MS) method in accordance with international standards. Liquid chromatography\u2013quadrupole time\u2010of\u2010flight mass spectrometry (LC\u2013QTOF\/MS) has enabled the determination of representative fragment ion patterns. The validated method was applied to 95 real samples, including 11 foods, 40 dietary supplements, and 44 counterfeit drugs. The overall detection rate was 38.9%, with the highest rate observed in counterfeit drugs (81.8%), followed by dietary supplements (2.5%), whereas no AAS were detected in foods. When classified by formulation, injectables showed the highest detection rate (100.0%), followed by liquids (78.6%), tablets (58.3%), powders (20.0%), and capsules (3.3%). Frequently detected compounds included testosterone\u201017\u2010propionate (0.001\u2013119, 850.0\u2009\u03bcg\/g), testosterone\u201017\u2010isocaproate (0.002\u20131442.7\u2009\u03bcg\/g), and nandrolone decanoate (0.01\u2013120,023.0\u2009\u03bcg\/g). Anastrozole and exemestane, which are not currently included as LC\u2013MS\/MS target compounds, were also identified through LC\u2013QTOF\/MS. Furthermore, LC\u2013QTOF\/MS results revealed the presence of nonsteroidal compounds, including phosphodiesterase\u20105 inhibitors and weight\u2010loss compounds, indicating potential health risks associated with the combined pharmacological effects of these substances. The analytical method developed in this study can be effectively used for both screening and quantification and offers practical applicability to regulatory monitoring and enhancement of public health protection.<\/jats:p>","DOI":"10.1002\/dta.70069","type":"journal-article","created":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T06:46:06Z","timestamp":1775457966000},"page":"756-770","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Screening of Anabolic Androgenic Steroids in Illicit Dietary Supplements and Counterfeit Drugs Using LC\u2013MS\/MS and LC\u2013QTOF\/MS"],"prefix":"10.1002","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4700-9673","authenticated-orcid":false,"given":"Hyunsuk","family":"Kim","sequence":"first","affiliation":[{"name":"Advanced Analysis Division, Toxicological Evaluation and Research Department National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety  Cheongju Chungcheongbuk\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1274-6587","authenticated-orcid":false,"given":"Sowoon","family":"Seo","sequence":"additional","affiliation":[{"name":"Advanced Analysis Division, Toxicological Evaluation and Research Department National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety  Cheongju Chungcheongbuk\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5236-5995","authenticated-orcid":false,"given":"Aeseul","family":"Kim","sequence":"additional","affiliation":[{"name":"Advanced Analysis Division, Toxicological Evaluation and Research Department National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety  Cheongju Chungcheongbuk\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5995-4579","authenticated-orcid":false,"given":"Hyung\u00a0Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Advanced Analysis Division, Toxicological Evaluation and Research Department National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety  Cheongju Chungcheongbuk\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9241-2986","authenticated-orcid":false,"given":"Hyun\u2010Kyung","family":"Kim","sequence":"additional","affiliation":[{"name":"Advanced Analysis Division, Toxicological Evaluation and Research Department National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety  Cheongju Chungcheongbuk\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8526-7377","authenticated-orcid":false,"given":"Geum\u00a0Joo","family":"Yoo","sequence":"additional","affiliation":[{"name":"Advanced Analysis Division, Toxicological Evaluation and Research Department National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety  Cheongju Chungcheongbuk\u2010do Republic of 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