{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T18:37:38Z","timestamp":1783017458674,"version":"3.54.6"},"reference-count":41,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T00:00:00Z","timestamp":1778371200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T00:00:00Z","timestamp":1778371200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug Testing and Analysis"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are synthetic chemicals used in a wide range of consumer and industrial products. Their chemical stability and resistance to degradation lead to environmental persistence, raising concerns about human exposure and health risks. Although PFAS have been extensively monitored in ecological and traditional biological matrices, limited research has studied their presence in human hair. This study aimed to evaluate PFAS exposure in a New York population and contribute to the growing evidence supporting hair as a viable matrix for PFAS biomonitoring. A quantitative LC\u2010MS\/MS method for PFOA, PFNA, and PFHpA in human hair was validated according to ANSI\/ASB Standard 036 guidelines, demonstrating linearity across a calibration range of 0.3\u201325\u2009pg\/mg. Real\u2010case hair samples (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200926), collected from individuals living in New York, were analyzed using LC\u2010MS\/MS. PFHpA was detected in 100% of the samples, with a median concentration of 14.11\u2009pg\/mg. In contrast, PFOA and PFNA were detected in 30.8% and 7.7% of samples, respectively, with median concentrations of 0.15\u2009pg\/mg for both compounds. The New York cohort had a unique PFAS profile, with lower PFOA and PFNA detection than some Asian cohorts but higher PFHpA levels than European and Asian studies. These findings highlight ongoing human exposure to legacy and emerging PFAS, demonstrating the utility of hair as a tool for monitoring chemical exposure trends. This research underscores the importance of ongoing PFAS surveillance to inform environmental health initiatives, guide regulatory efforts, and protect populations at potential elevated risk due to occupation, geography, or socioeconomic factors.\n                  <\/jats:p>","DOI":"10.1002\/dta.70087","type":"journal-article","created":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T03:21:01Z","timestamp":1778469661000},"page":"893-904","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Advancing PFAS Biomonitoring in Hair: Rapid Analytical Method and Global Comparison of US Exposure"],"prefix":"10.1002","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0396-6723","authenticated-orcid":false,"given":"Ashef","family":"Ameer","sequence":"first","affiliation":[{"name":"Department of Sciences, John Jay College of Criminal Justice City University of New York  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7842-5484","authenticated-orcid":false,"given":"Justin","family":"Allen","sequence":"additional","affiliation":[{"name":"Department of Sciences, John Jay College of Criminal Justice City University of New York  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6111-6176","authenticated-orcid":false,"given":"Teeshavi","family":"Acosta","sequence":"additional","affiliation":[{"name":"Department of Sciences, John Jay College of Criminal Justice City University of New York  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3858-1280","authenticated-orcid":false,"given":"Marta","family":"Concheiro\u2010Guisan","sequence":"additional","affiliation":[{"name":"Department of Sciences, John Jay College of Criminal Justice City University of New York  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3224-9738","authenticated-orcid":false,"given":"Ana\u00a0Miguel\u00a0Fonseca","family":"Pego","sequence":"additional","affiliation":[{"name":"Department of Sciences, John Jay College of Criminal Justice City University of New York  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ieam.258"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph182010900"},{"key":"e_1_2_10_4_1","first-page":"1","volume-title":"Fluorinated Polymers: Applications","author":"Dams R.","year":"2016"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0EM00291G"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1306615"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxics13020134"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2011.11.015"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216\u2010011\u20105660\u20105"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2012.12.002"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2015.07.009"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2017.02.077"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jes.2017.08.017"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2018.04.279"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2019.04.195"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00244\u2010020\u201000743\u2010w"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2020.116219"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2021.122651"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2021.152849"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2020.121499"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph120606098"},{"key":"e_1_2_10_22_1","unstructured":"Environmental Protection Agency \u201cPFAS Structures List. CompTox Chemicals Dashboard \u201d accessed March 7 2025 https:\/\/comptox.epa.gov\/dashboard\/chemical\u2010lists\/PFASSTRUCT."},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22030995"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2016.05.221"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2013.06.022"},{"key":"e_1_2_10_26_1","unstructured":"AAFS Standards Board \u201cANSI\/ASB Standard 036 First Edition: Standard Practices for Method Validation in Forensic Toxicology \u201d (2019). AAFS Standards Boardhttps:\/\/www.aafs.org\/sites\/default\/files\/media\/documents\/036_Std_e1.pdf."},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2011.09.009"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/10253890.2018.1458088"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0379\u20100738(99)00146\u20102"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.0c00255"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2006.02.019"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.3741"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2014.08.039"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2019.108648"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2011.07.005"},{"key":"e_1_2_10_36_1","unstructured":"Environmental Working Group \u201cEWG Tap Water Database: New York. EWG Tap Water Database \u201d accessed July 7 2025 https:\/\/www.ewg.org\/tapwater\/state.php?stab=NY#overview."},{"issue":"90","key":"e_1_2_10_37_1","first-page":"39124","article-title":"Designation of Perfluorooctanoic Acid (PFOA) and Perfluorooctanesulfonic Acid (PFOS) as CERCLA Hazardous Substances","volume":"89","author":"Environmental Protection Agency","year":"2024","journal-title":"Federal Register"},{"key":"e_1_2_10_38_1","unstructured":"United Nations Environment Programme \u201cStockholm Convention on Persistent Organic Pollutants \u201d accessed May 11 2025 pops.int https:\/\/www.pops.int\/."},{"key":"e_1_2_10_39_1","unstructured":"European Chemicals Agency \u201cPerfluoroalkyl Chemicals (PFAS) \u201d accessed April 19 2025. European Chemicals Agency https:\/\/echa.europa.eu\/hot\u2010topics\/perfluoroalkyl\u2010chemicals\u2010pfas."},{"key":"e_1_2_10_40_1","unstructured":"G.Dagorn R.Aubert S.Horel L.Martinon andT.Steffen \u201cForever Pollution: Explore the Map of Europe's PFAS Contamination \u201d (2023) Le Monde https:\/\/www.lemonde.fr\/en\/les\u2010decodeurs\/article\/2023\/02\/23\/forever\u2010pollution\u2010explore\u2010the\u2010map\u2010of\u2010europe\u2010s\u2010pfas\u2010contamination_6016905_8.html."},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1080\/02757540902918321"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.4491\/KSEE.2025.47.6.410"}],"container-title":["Drug Testing and Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dta.70087","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dta.70087","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dta.70087","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T17:37:00Z","timestamp":1783013820000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/dta.70087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,10]]},"references-count":41,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/dta.70087"],"URL":"https:\/\/doi.org\/10.1002\/dta.70087","archive":["Portico"],"relation":{},"ISSN":["1942-7603","1942-7611"],"issn-type":[{"value":"1942-7603","type":"print"},{"value":"1942-7611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,10]]},"assertion":[{"value":"2025-12-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}