{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:56:51Z","timestamp":1790895411803,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug Testing and Analysis"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This publication describes the analytical characterization of ZC\u2010B (3\u2010(4\u2010bromo\u20102,5\u2010dimethoxyphenyl)azetidine, also termed 2C\u2010B\u2010AZET), a novel hallucinogenic substance identified in capsules seized from drug\u2010related cases. The off\u2010white powder recovered from inside the capsules was used without further purification and systematically analyzed using gas chromatography\u2013mass spectrometry (GC\u2013MS), ultra\u2010high\u2010performance liquid chromatography\u2010quadrupole time\u2010of\u2010flight mass spectrometry (UHPLC\u2010QTOF\u2010MS), Fourier\u2010transform infrared spectroscopy (FTIR) and nuclear magnetic resonance spectroscopy (NMR). Following GC\u2013MS analysis, ZC\u2010B exhibited characteristic fragment ions involving the bromine isotopes at\n                    <jats:italic>m\/z<\/jats:italic>\n                    242\/244,\n                    <jats:italic>m\/z<\/jats:italic>\n                    226\/228, and\n                    <jats:italic>m\/z<\/jats:italic>\n                    148. The molecular ion could only be observed at very low intensity. Under UHPLC\u2010QTOF\u2010MS\/MS conditions, the protonated molecule was detected at\n                    <jats:italic>m\/z<\/jats:italic>\n                    272.0282. The predominant product ions in auto\u2010MS\/MS mode were\n                    <jats:italic>m\/z<\/jats:italic>\n                    228.9860 and 198.9752. A search of the mass spectrometry data against the NIST spectral library yielded no matching results. The off\u2010white solid recovered from inside the capsules was directly characterized by NMR spectroscopy for full structural elucidation. Comparison with recent literature unambiguously identified the substance as ZC\u2010B succinate. This established analytical framework was simple and well\u2010suited for the qualitative detection of ZC\u2010B in forensic drug seizures. Furthermore, it serves as a reference for the detection and identification of emerging new psychoactive substances (NPS).\n                  <\/jats:p>","DOI":"10.1002\/dta.70155","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:40:43Z","timestamp":1790894443000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Forensic Identification and Structural Characterization of ZC\u2010B: A New Azetidine 2C\u2010Series Phenethylamine From Illicit Seized Capsules"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6662-8584","authenticated-orcid":false,"given":"Hong","family":"Song","sequence":"first","affiliation":[{"name":"National Narcotics Laboratory Zhejiang Regional Center  Hangzhou Zhejiang China"},{"name":"Key Laboratory of Drug Prevention and Control Technology of Zhejiang Province  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3497-2463","authenticated-orcid":false,"given":"Luyi","family":"Zeng","sequence":"additional","affiliation":[{"name":"School of Pharmacy China Pharmaceutical University  Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Wu","sequence":"additional","affiliation":[{"name":"National Narcotics Laboratory Zhejiang Regional Center  Hangzhou Zhejiang China"},{"name":"Key Laboratory of Drug Prevention and Control Technology of Zhejiang Province  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4846-8449","authenticated-orcid":false,"given":"Haixing","family":"Wang","sequence":"additional","affiliation":[{"name":"National Narcotics Laboratory Zhejiang Regional Center  Hangzhou Zhejiang China"},{"name":"Key Laboratory of Drug Prevention and Control Technology of Zhejiang Province  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Yuan","sequence":"additional","affiliation":[{"name":"Criminal Science and Technology Brigade of Rizhao Municipal Public Security Bureau  Rizhao Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongjian","family":"Zhang","sequence":"additional","affiliation":[{"name":"National Narcotics Laboratory Zhejiang Regional Center  Hangzhou Zhejiang China"},{"name":"Key Laboratory of Drug Prevention and Control Technology of Zhejiang Province  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhong","family":"Gao","sequence":"additional","affiliation":[{"name":"National Narcotics Laboratory Zhejiang Regional Center  Hangzhou Zhejiang China"},{"name":"Key Laboratory of Drug Prevention and Control Technology of Zhejiang Province  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,1]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11419\u2010022\u201000638\u20106"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.2371"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/7854_2017_475"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.2446"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.2675"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2019.01423"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2018.10.037"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2016.05.001"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2007.01.008"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43440\u2010023\u201000539\u20104"},{"key":"e_1_2_9_12_1","volume-title":"PIHKAL: A Chemical Love Story","author":"Shulgin A. 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