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During mouse embryogenesis, <jats:italic>Eaf2<\/jats:italic> is preferentially expressed in the central nervous system and in sensory and neuroendocrine organs, including the brain, spinal cord, cranial and spinal ganglia, developing otocyst, the retina, and the pituitary. <jats:italic>Eaf2<\/jats:italic> transcripts were also found in sites where active epithelium\u2013mesenchymal interactions are occurring. These included the invaginating tooth buds, mammary gland anlage, submandibular glands, the lung, the pancreas, and the kidney. Other sites of expression included bladder and intestine. In the developing lens, <jats:italic>Eaf2<\/jats:italic> transcripts were absent in the proliferating anterior lens epithelial cells but were present in the terminally differentiated primary lens fiber cells and also in nonproliferating lens fiber cells in the equatorial zone where lens epithelial cells withdraw from cell cycle and terminally differentiate into secondary lens fiber cells. This spatially restricted pattern of <jats:italic>Eaf2<\/jats:italic> expression in the developing lens suggests that <jats:italic>Eaf2<\/jats:italic> may play an important role in regulating lens maturation. Developmental Dynamics 228:273\u2013280, 2003. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dvdy.10367","type":"journal-article","created":{"date-parts":[[2003,9,25]],"date-time":"2003-09-25T05:40:35Z","timestamp":1064468435000},"page":"273-280","source":"Crossref","is-referenced-by-count":21,"title":["Expression of murine ELL\u2010associated factor 2 (<i>Eaf2<\/i>) is developmentally 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