{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:56:28Z","timestamp":1787064988005,"version":"build-2736575974"},"reference-count":44,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2001,4,27]],"date-time":"2001-04-27T00:00:00Z","timestamp":988329600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Developmental Dynamics"],"published-print":{"date-parts":[[2001,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>During development of the vertebrate neural retina, multipotent stem cells give rise to retinal neurons as well as to M\u00fcller cells, the principal glial population in the retina. Recent studies have shed light upon the extracellular and intracellular signaling pathways that regulate M\u00fcller glial cell genesis. Emerging evidence demonstrates that activation of the Notch signaling pathway can play a role in regulating M\u00fcller cell development as well as gliogenesis in other parts of the central nervous system. Cyclin dependent kinase (CDK) inhibitors of the Cip\/Kip subfamily are cell cycle regulators that can regulate progenitor proliferation during retinal development, but also regulate the proliferation of M\u00fcller glia when they become activated in response to stress or injury. Surprisingly this class of proteins can also promote the development of M\u00fcller glia. In this review we discuss the role of both Notch and the CDK inhibitors in regulating M\u00fcller cell development. \u00a9 2001 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dvdy.1145","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T18:10:13Z","timestamp":1030299013000},"page":"146-153","source":"Crossref","is-referenced-by-count":34,"title":["Becoming glial in the neural retina"],"prefix":"10.1002","volume":"221","author":[{"given":"Monica L.","family":"Vetter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn 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