{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T11:34:20Z","timestamp":1775302460650,"version":"3.50.1"},"reference-count":57,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,10,28]],"date-time":"2005-10-28T00:00:00Z","timestamp":1130457600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Developmental Dynamics"],"published-print":{"date-parts":[[2006,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The establishment of polarity in <jats:italic>Drosophila<\/jats:italic> requires the correct specification of the oocyte in early stages of oogenesis, its positioning at the posterior of the egg chamber, and signalling events between the oocyte and the adjacent posterior follicle cells. As a consequence, the anterior\u2010posterior and the dorsal\u2010ventral axes are fixed. The posterior localisation of the oocyte depends on cadherin\u2010mediated adhesion between the oocyte and the follicle cells. Here we show that <jats:italic>dicephalic<\/jats:italic> mutants affect the posterior positioning of the oocyte without interfering with oocyte specification in the germarium. Unlike other mutants that also affect the posterior placement of the oocyte, <jats:italic>dicephalic<\/jats:italic> mutants affect neither <jats:italic>gurken<\/jats:italic> expression nor karyosome formation during meiosis. By analysing in detail the mutant phenotypes of <jats:italic>dicephalic<\/jats:italic>, we find that cyst formation in mutant germaria is defective and that it shares some similarities with cysts that lack <jats:italic>D<\/jats:italic>E\u2010cadherin in the germline cells. We propose a model in which <jats:italic>dicephalic<\/jats:italic> is involved in the proper adhesion between the oocyte and the somatic follicle cells. Developmental Dynamics 235:908\u2013917, 2006.  \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dvdy.20620","type":"journal-article","created":{"date-parts":[[2005,10,28]],"date-time":"2005-10-28T12:46:30Z","timestamp":1130503590000},"page":"908-917","source":"Crossref","is-referenced-by-count":7,"title":["A novel mutant phenotype implicates <i>dicephalic<\/i> in cyst formation in the <i>Drosophila<\/i> ovary"],"prefix":"10.1002","volume":"235","author":[{"given":"Ruth","family":"McCaffrey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"St 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