{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:40:25Z","timestamp":1786977625211,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2006,5,11]],"date-time":"2006-05-11T00:00:00Z","timestamp":1147305600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Developmental Dynamics"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\u03b1N\u2010catenin is a cadherin\u2010binding protein, widely expressed in the nervous system; and it plays a crucial role in cadherin\u2010mediated cell\u2010cell adhesion. Here we report the effects of \u03b1N\u2010catenin gene deficiency on brain morphogenesis. In addition to the previously reported phenotypes, we found that some of the axon tracts did not normally develop, in particular, axons of the anterior commissure failed to cross the midline, migrating, rather, to ectopic places. In restricted nuclei, a population of neurons was missing or their laminar arrangement was distorted. The ventricular structures were also deformed. These results indicate that \u03b1N\u2010catenin has diverse roles in the organization of the central nervous system, but only in limited portions of the brain. Developmental Dynamics 235:2559\u20132566, 2006. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dvdy.20841","type":"journal-article","created":{"date-parts":[[2006,5,12]],"date-time":"2006-05-12T05:37:33Z","timestamp":1147412253000},"page":"2559-2566","source":"Crossref","is-referenced-by-count":35,"title":["\u03b1N\u2010catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain"],"prefix":"10.1002","volume":"235","author":[{"given":"Masato","family":"Uemura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masatoshi","family":"Takeichi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,5,11]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1212"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devbrainres.2005.08.004"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0361-9230(92)90146-O"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1699"},{"key":"e_1_2_5_6_1","first-page":"379","article-title":"Differential expression of alpha N\u2010catenin and N\u2010cadherin during early development of chicken embryos","volume":"38","author":"Hirano S","year":"1994","journal-title":"Int J Dev Biol"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(92)90103-J"},{"key":"e_1_2_5_8_1","doi-asserted-by":"crossref","first-page":"3177","DOI":"10.1242\/jcs.114.17.3177","article-title":"alphaT\u2010catenin: a novel tissue\u2010specific beta\u2010catenin\u2010binding protein mediating strong cell\u2010cell adhesion","volume":"114","author":"Janssens B","year":"2001","journal-title":"J Cell Sci"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80392-X"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1433"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1121449"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-06-02265.2003"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1006\/geno.2000.6322"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng908"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/gene.10024"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2005.12.057"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1006\/mcne.1997.0626"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(02)00748-1"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.3.901"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.1994.1124"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(01)00246-X"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.127.1.247"}],"container-title":["Developmental Dynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdvdy.20841","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dvdy.20841","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T12:49:47Z","timestamp":1760359787000},"score":1,"resource":{"primary":{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/10.1002\/dvdy.20841"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5,11]]},"references-count":21,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["10.1002\/dvdy.20841"],"URL":"https:\/\/doi.org\/10.1002\/dvdy.20841","archive":["Portico"],"relation":{},"ISSN":["1058-8388","1097-0177"],"issn-type":[{"value":"1058-8388","type":"print"},{"value":"1097-0177","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,5,11]]}}}