{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T06:56:12Z","timestamp":1760424972540,"version":"build-2065373602"},"reference-count":38,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2009,12,23]],"date-time":"2009-12-23T00:00:00Z","timestamp":1261526400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Developmental Dynamics"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Anthrax Toxin Receptor 1<\/jats:italic> (<jats:italic>ANTXR1<\/jats:italic>; also known as <jats:italic>Tumor Endothelial Marker 8<\/jats:italic>, <jats:italic>TEM8<\/jats:italic>) is one of several genes that was recently found to be up\u2010regulated in tumor\u2010associated endothelial cells. In vitro, the protein can link extracellular matrix components with the actin cytoskeleton to promote cell adhesion and cell spreading. Both, ANTXR1 and the closely related ANTXR2 can bind anthrax toxin and interact with lipoprotein receptor\u2010related protein 5 and 6, which also work as coreceptors in the WNT signaling pathway. Here, we report the cloning of chick <jats:italic>ANTXR1<\/jats:italic> from a suppression subtractive hybridization screen for fibroblast growth factor (FGF) \u2010inducible genes in chicken embryonic facial mesenchyme. We show that chicken <jats:italic>ANTXR1<\/jats:italic> is dynamically expressed throughout embryogenesis, starting from Hamburger and Hamilton stage 10. Furthermore, we demonstrate that FGF signaling is sufficient, but not necessary, to induce <jats:italic>ANTXR1<\/jats:italic> expression in chicken facial mesenchyme. Developmental Dynamics 239:680\u2013687, 2010. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dvdy.22194","type":"journal-article","created":{"date-parts":[[2009,12,23]],"date-time":"2009-12-23T15:12:29Z","timestamp":1261581149000},"page":"680-687","source":"Crossref","is-referenced-by-count":7,"title":["Expression and regulation of <i>ANTXR1<\/i> in the chick embryo"],"prefix":"10.1002","volume":"239","author":[{"given":"David","family":"Herrmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Ferrer\u2010Vaquer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Lahsnig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Firnberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Leibbrandt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annette","family":"Neub\u00fcser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,1,22]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2008.01226.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.00538"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00582.2004"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/n35101999"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M307900200"},{"key":"e_1_2_5_7_1","first-page":"6649","article-title":"Cell 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