{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T11:04:36Z","timestamp":1761217476756,"version":"build-2065373602"},"reference-count":21,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2011,7,14]],"date-time":"2011-07-14T00:00:00Z","timestamp":1310601600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Developmental Dynamics"],"published-print":{"date-parts":[[2011,8]]},"abstract":"Abstract<\/jats:title>Fermitin genes are highly conserved and encode cytocortex proteins that mediate integrin signalling. Fermitin 1 (Kindlin1) is implicated in Kindler syndrome, a human skin blistering disorder. We report the isolation of the three Fermitin orthologs from Xenopus laevis<\/jats:italic> embryos and describe their developmental expression patterns. Fermitin 1<\/jats:italic> is expressed in the skin, otic and olfactory placodes, pharyngeal arches, pronephric duct, and heart. Fermitin 2<\/jats:italic> is restricted to the somites and neural crest. Fermitin 3<\/jats:italic> is expressed in the notochord, central nervous system, cement gland, ventral blood islands, vitelline veins, and myeloid cells. Our findings are consistent with the view that Fermitin 1 is generally expressed in the skin, Fermitin 2 in muscle, and Fermitin 3 in hematopoietic lineages. Moreover, we describe novel sites of Fermitin gene expression that extend our knowledge of this family. Our data provide a basis for further functional analysis of the Fermitin family in Xenopus laevis<\/jats:italic>. Developmental Dynamics 240:1958\u20131963, 2011. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dvdy.22683","type":"journal-article","created":{"date-parts":[[2011,7,14]],"date-time":"2011-07-14T15:59:20Z","timestamp":1310659160000},"page":"1958-1963","source":"Crossref","is-referenced-by-count":4,"title":["Developmental expression of the fermitin\/kindlin gene family in Xenopus laevis<\/i> embryos"],"prefix":"10.1002","volume":"240","author":[{"given":"Claire A.","family":"Canning","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica Sze Ki","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John E. A.","family":"Common","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. 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