{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T06:53:20Z","timestamp":1780383200597,"version":"3.54.1"},"reference-count":22,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T00:00:00Z","timestamp":1599091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000098","name":"NIH Clinical Center","doi-asserted-by":"publisher","award":["NIH CA009299"],"award-info":[{"award-number":["NIH CA009299"]}],"id":[{"id":"10.13039\/100000098","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000098","name":"NIH Clinical Center","doi-asserted-by":"publisher","award":["NIH CA16672"],"award-info":[{"award-number":["NIH CA16672"]}],"id":[{"id":"10.13039\/100000098","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000098","name":"NIH Clinical Center","doi-asserted-by":"publisher","award":["NIH GM56929"],"award-info":[{"award-number":["NIH GM56929"]}],"id":[{"id":"10.13039\/100000098","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000098","name":"NIH Clinical Center","doi-asserted-by":"publisher","award":["NIH HD030284"],"award-info":[{"award-number":["NIH HD030284"]}],"id":[{"id":"10.13039\/100000098","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000098","name":"NIH Clinical Center","doi-asserted-by":"publisher","award":["NIH U54 HD083092"],"award-info":[{"award-number":["NIH U54 HD083092"]}],"id":[{"id":"10.13039\/100000098","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["anatomypubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Developmental Dynamics"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The uterus is the location where multiple events occur that are required for the start of new life in mammals. The adult uterus contains endometrial or uterine glands that are essential for female fertility. In the mouse, uterine glands are located in the lateral and antimesometrial regions of the uterine horn. Previous three\u2010dimensional (3D)\u2010imaging of the adult uterus, its glands, and implanting embryos has been performed by multiple groups, using fluorescent microscopy. Adenogenesis, the formation of uterine glands, initiates after birth. Recently, we created a 3D\u2010staging system of mouse uterine gland development at postnatal time points, using light sheet fluorescent microscopy. Here, using a similar approach, we examine the morphological changes in the epithelium of the perinatal mouse uterus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The uterine epithelium exhibits dorsoventral (mesometrial\u2010antimesometrial) patterning as early as 3\u2009days after birth (P3), marked by the presence of the dorsally positioned developing uterine rail. Uterine gland buds are present beginning at P4. Novel morphological epithelial structures, including a ventral ridge and uterine segments were identified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The perinatal mouse uterine luminal epithelium develops dorsal\u2010ventral morphologies at 3 to 4\u2009days postpartum. Between 5 and 6\u2009days postpartum uterine epithelial folds form, defining alternating left\u2010right segments.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dvdy.234","type":"journal-article","created":{"date-parts":[[2020,8,6]],"date-time":"2020-08-06T23:40:38Z","timestamp":1596757238000},"page":"1377-1386","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Epithelial morphogenesis in the perinatal mouse uterus"],"prefix":"10.1002","volume":"249","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3502-8906","authenticated-orcid":false,"given":"Zer","family":"Vue","sequence":"first","affiliation":[{"name":"Program in Developmental Biology Baylor College of Medicine  Houston Texas USA"},{"name":"Department of Genetics University of Texas MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard R.","family":"Behringer","sequence":"additional","affiliation":[{"name":"Program in Developmental Biology Baylor College of Medicine  Houston Texas USA"},{"name":"Department of Genetics University of Texas MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod65.5.1311"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.111.097089"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2001.0458"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.111.097188"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001860102"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-117-5-2229"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.103.026336"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0264.2006.00727.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.03.008"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.144386"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03092-4"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrd.22973"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.77.7.4113"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1225"},{"key":"e_1_2_6_16_1","first-page":"287","article-title":"Uterine differentiation as a foundation for subsequent fertility","volume":"54","author":"Bartol FF","year":"1999","journal-title":"J Reprod Fertil Suppl"},{"key":"e_1_2_6_17_1","first-page":"99","article-title":"Early uterine development in pigs","volume":"48","author":"Bartol FF","year":"1993","journal-title":"J Reprod Fertil Suppl"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2017.01.015"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.113.107631"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.113.111971"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2017.05.022"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1210054"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2018.08.006"}],"container-title":["Developmental 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