{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T08:50:03Z","timestamp":1789203003982,"version":"build-2803163510"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,3,27]],"date-time":"2013-03-27T00:00:00Z","timestamp":1364342400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Developmental Dynamics"],"published-print":{"date-parts":[[2013,5]]},"abstract":"\n Background:<\/jats:styled-content>\n The axial skeleton develops from the sclerotome, a mesenchymal cell population derived from somites. Sclerotomal cells migrate from somites to the perinotochordal and perineural space where they differentiate into chondrocytes to form cartilage and bone. In anurans, little is known about the way how the sclerotome changes as development proceeds and how these events are regulated at the molecular level.\n Pax1<\/jats:italic>\n ,\n Pax9<\/jats:italic>\n , and\n Uncx4.1<\/jats:italic>\n genes play a central role in the morphogenesis of the axial skeleton in vertebrates, regulating cell proliferation and chondrogenic specification of the sclerotome.\n Results:<\/jats:styled-content>\n In this work, we cloned and examined through whole\u2010mount\n in situ<\/jats:italic>\n hybridization and reverse transcriptase\u2010polymerase chain reaction the expression patterns of\n pax1<\/jats:italic>\n ,\n pax9<\/jats:italic>\n , and\n uncx<\/jats:italic>\n transcription factors in the anuran\n Xenopus laevis<\/jats:italic>\n .\n Conclusions:<\/jats:styled-content>\n We found that these genes are similarly expressed in the sclerotome and in the pharyngeal pouch. A detailed analysis of the location of these transcripts showed that they are expressed in different subdomains of the sclerotomal compartment and differ from that observed in other vertebrates.\n Developmental Dynamics 242:562\u2013569, 2013<\/jats:italic>\n . \u00a9 2013 Wiley Periodicals, Inc.\n <\/jats:p>","DOI":"10.1002\/dvdy.23945","type":"journal-article","created":{"date-parts":[[2013,2,9]],"date-time":"2013-02-09T01:14:46Z","timestamp":1360372486000},"page":"572-579","source":"Crossref","is-referenced-by-count":30,"title":["Characterization of\n pax1<\/i>\n ,\n pax9<\/i>\n , and\n uncx<\/i>\n sclerotomal genes during\n Xenopus laevis<\/i>\n embryogenesis"],"prefix":"10.1002","volume":"242","author":[{"given":"Romel Sebasti\u00e1n","family":"S\u00e1nchez","sequence":"first","affiliation":[{"name":"Departamento de Biolog\u00eda del Desarrollo San Miguel de Tucum\u00e1n Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara 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