{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:20:49Z","timestamp":1790961649995,"version":"4.1.0"},"reference-count":153,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,12,11]],"date-time":"2015-12-11T00:00:00Z","timestamp":1449792000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The National Institute of Dental and Craniofacial Research, NIH","award":["DE024759"],"award-info":[{"award-number":["DE024759"]}]},{"name":"The UTHealth School of Dentistry"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Developmental Dynamics"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:p>The morphogenesis of midfacial processes requires the coordination of a variety of cellular functions of both mesenchymal and epithelial cells to develop complex structures. Any failure or delay in midfacial development as well as any abnormal fusion of the medial and lateral nasal and maxillary prominences will result in developmental defects in the midface with a varying degree of severity, including cleft, hypoplasia, and midline expansion. Despite the advances in human genome sequencing technology, the causes of nearly 70% of all birth defects, which include midfacial development defects, remain unknown. Recent studies in animal models have highlighted the importance of specific signaling cascades and genetic\u2010environmental interactions in the development of the midfacial region. This review will summarize the current understanding of the morphogenetic processes and molecular mechanisms underlying midfacial birth defects based on mouse models with midfacial developmental abnormalities. <jats:italic>Developmental Dynamics 245:276\u2013293, 2016<\/jats:italic>. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/dvdy.24368","type":"journal-article","created":{"date-parts":[[2015,11,12]],"date-time":"2015-11-12T11:10:41Z","timestamp":1447326641000},"page":"276-293","source":"Crossref","is-referenced-by-count":71,"title":["Molecular mechanisms of midfacial developmental defects"],"prefix":"10.1002","volume":"245","author":[{"given":"Akiko","family":"Suzuki","sequence":"first","affiliation":[{"name":"Department of Diagnostic &amp; Biomedical Sciences, School of Dentistry The University of Texas Health Science Center at Houston Houston Texas"},{"name":"Center for Craniofacial Research The University of Texas Health Science Center at Houston Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhruvee R.","family":"Sangani","sequence":"additional","affiliation":[{"name":"Center for Craniofacial Research The University of Texas Health Science Center at Houston Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afreen","family":"Ansari","sequence":"additional","affiliation":[{"name":"Center for Craniofacial Research The University of Texas Health Science Center at Houston Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junichi","family":"Iwata","sequence":"additional","affiliation":[{"name":"Department of Diagnostic &amp; Biomedical Sciences, School of Dentistry The University of Texas Health Science Center at Houston Houston Texas"},{"name":"Center for Craniofacial Research The University of Texas Health Science Center at Houston Houston Texas"},{"name":"The University of Texas Graduate School of Biomedical Sciences at Houston Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.162356199"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.129.21.4975"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2011.088864"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddr613"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.00581"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4773(00)00518-9"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1196-353"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.128.20.3975"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.018275"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.128.8.1253"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2011.10.001"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200112000-00030"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq030"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-386499-4.00001-X"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2005.034827"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.02395"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.20833"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.109.101055"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/383407a0"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2009.04.021"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(03)00088-5"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0009-9163.2004.00225.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1002927"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1415"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0603730103"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-6343.2007.00388.x"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2010.07.020"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0070-2153(05)66003-6"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2006.05.030"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2336223100"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90627-3"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI28988"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.01168-07"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2011.08.005"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2009.01.017"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-006-9000-6"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2005.12.022"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9969(99)00101-6"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.277.5329.1109"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdrc.20180"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2012.11.014"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0016672300000094"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80919-8"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1003851"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1999.79.4.1283"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.01705"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2014.01.019"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2015.02.010"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2012.05.026"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2005.06.005"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1002999"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.026583"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1093\/jmcb\/mjq008"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddr575"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1003949"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.02072"},{"key":"e_1_2_6_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2011.01806.x"},{"key":"e_1_2_6_59_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI61498"},{"key":"e_1_2_6_60_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddt410"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.1387\/ijdb.120191kv"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1190304"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.20646"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.075796"},{"key":"e_1_2_6_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2010.235"},{"key":"e_1_2_6_66_1","doi-asserted-by":"publisher","DOI":"10.1177\/10454411950060040601"},{"key":"e_1_2_6_67_1","doi-asserted-by":"publisher","DOI":"10.4161\/sgtp.29846"},{"key":"e_1_2_6_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2013.07.007"},{"key":"e_1_2_6_69_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1101347108"},{"key":"e_1_2_6_70_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0089448"},{"key":"e_1_2_6_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32814"},{"key":"e_1_2_6_72_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.01879"},{"key":"e_1_2_6_73_1","doi-asserted-by":"publisher","DOI":"10.4161\/org.4.2.5851"},{"key":"e_1_2_6_74_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320440210"},{"key":"e_1_2_6_75_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2004.00171.x"},{"key":"e_1_2_6_76_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/134.11.3106"},{"key":"e_1_2_6_77_1","doi-asserted-by":"publisher","DOI":"10.1159\/000056833"},{"key":"e_1_2_6_78_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI72688"},{"key":"e_1_2_6_79_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.20723"},{"key":"e_1_2_6_80_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.028167"},{"key":"e_1_2_6_81_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddr329"},{"key":"e_1_2_6_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mod.2008.06.003"},{"key":"e_1_2_6_83_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddt369"},{"key":"e_1_2_6_84_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201110049"},{"key":"e_1_2_6_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2014.05.009"},{"key":"e_1_2_6_86_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.01676"},{"key":"e_1_2_6_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2013.09.013"},{"key":"e_1_2_6_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.22072"},{"key":"e_1_2_6_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(04)00153-4"},{"key":"e_1_2_6_90_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.115.1.133"},{"key":"e_1_2_6_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60695-4"},{"key":"e_1_2_6_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2003.10.033"},{"key":"e_1_2_6_93_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2005.01176.x"},{"key":"e_1_2_6_94_1","doi-asserted-by":"publisher","DOI":"10.1387\/ijdb.052101xn"},{"key":"e_1_2_6_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mod.2010.12.002"},{"key":"e_1_2_6_96_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.129.15.3563"},{"key":"e_1_2_6_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/78140"},{"key":"e_1_2_6_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2012.12.003"},{"key":"e_1_2_6_99_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.23.13714"},{"key":"e_1_2_6_100_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034512470830"},{"key":"e_1_2_6_101_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2013.00061"},{"key":"e_1_2_6_102_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.014829"},{"key":"e_1_2_6_103_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0037685"},{"key":"e_1_2_6_104_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI29872"},{"key":"e_1_2_6_105_1","doi-asserted-by":"publisher","DOI":"10.1677\/erc.0.0070165"},{"key":"e_1_2_6_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2011.02.027"},{"key":"e_1_2_6_107_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1103877108"},{"key":"e_1_2_6_108_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddg058"},{"key":"e_1_2_6_109_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-8628(20000703)93:1<22::AID-AJMG5>3.0.CO;2-U"},{"key":"e_1_2_6_110_1","doi-asserted-by":"publisher","DOI":"10.1309\/2JK279BU2G743MWJ"},{"key":"e_1_2_6_111_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.009274"},{"key":"e_1_2_6_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2012.01.019"},{"key":"e_1_2_6_113_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1533407"},{"key":"e_1_2_6_114_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0494-348"},{"key":"e_1_2_6_115_1","doi-asserted-by":"publisher","DOI":"10.1038\/74231"},{"key":"e_1_2_6_116_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.128.14.2755"},{"key":"e_1_2_6_117_1","doi-asserted-by":"publisher","DOI":"10.4161\/org.23307"},{"key":"e_1_2_6_118_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.116.2.297"},{"key":"e_1_2_6_119_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.052647"},{"key":"e_1_2_6_120_1","doi-asserted-by":"publisher","DOI":"10.1177\/10454411950060030301"},{"key":"e_1_2_6_121_1","doi-asserted-by":"publisher","DOI":"10.4161\/cam.4.4.12829"},{"key":"e_1_2_6_122_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.24.15.6635-6644.2004"},{"key":"e_1_2_6_123_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.037440"},{"key":"e_1_2_6_124_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.124.14.2691"},{"key":"e_1_2_6_125_1","doi-asserted-by":"publisher","DOI":"10.1159\/000337618"},{"key":"e_1_2_6_126_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1002224"},{"key":"e_1_2_6_127_1","doi-asserted-by":"publisher","DOI":"10.1177\/15353702-0323006-04"},{"key":"e_1_2_6_128_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.127.21.4519"},{"key":"e_1_2_6_129_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.13.14.1834"},{"key":"e_1_2_6_130_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.00241"},{"key":"e_1_2_6_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2006.11.107"},{"key":"e_1_2_6_132_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.012179"},{"key":"e_1_2_6_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2010.02.021"},{"key":"e_1_2_6_134_1","first-page":"541","article-title":"Origins and plasticity of neural crest cells and their roles in jaw and craniofacial evolution","volume":"47","author":"Trainor PA","year":"2003","journal-title":"Int J Dev Biol"},{"key":"e_1_2_6_135_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.13.23.3136"},{"key":"e_1_2_6_136_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddh034"},{"key":"e_1_2_6_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2004.11.067"},{"key":"e_1_2_6_138_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.463620"},{"key":"e_1_2_6_139_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1003785"},{"key":"e_1_2_6_140_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-213X-10-22"},{"key":"e_1_2_6_141_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.128.15.2953"},{"key":"e_1_2_6_142_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0177(199709)210:1<41::AID-AJA5>3.0.CO;2-1"},{"key":"e_1_2_6_143_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biophys-083012-130404"},{"key":"e_1_2_6_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2008.05.007"},{"key":"e_1_2_6_145_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-213X-10-48"},{"key":"e_1_2_6_146_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.01786"},{"key":"e_1_2_6_147_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.26.14536"},{"key":"e_1_2_6_148_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.00491"},{"key":"e_1_2_6_149_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvg.20728"},{"key":"e_1_2_6_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2010.01.039"},{"key":"e_1_2_6_151_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80324-4"},{"key":"e_1_2_6_152_1","doi-asserted-by":"publisher","DOI":"10.1038\/381238a0"},{"key":"e_1_2_6_153_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2006.04.005"},{"key":"e_1_2_6_154_1","doi-asserted-by":"publisher","DOI":"10.1086\/323703"}],"container-title":["Developmental Dynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdvdy.24368","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dvdy.24368","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T08:04:54Z","timestamp":1760342694000},"score":1,"resource":{"primary":{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/10.1002\/dvdy.24368"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,11]]},"references-count":153,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1002\/dvdy.24368"],"URL":"https:\/\/doi.org\/10.1002\/dvdy.24368","archive":["Portico"],"relation":{},"ISSN":["1058-8388","1097-0177"],"issn-type":[{"value":"1058-8388","type":"print"},{"value":"1097-0177","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,11]]}}}