{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T19:11:45Z","timestamp":1789931505116,"version":"4.0.1"},"reference-count":143,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:00:00Z","timestamp":1758758400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:00:00Z","timestamp":1758758400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["KAKENHI 24K19841"],"award-info":[{"award-number":["KAKENHI 24K19841"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["22K06295"],"award-info":[{"award-number":["22K06295"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["JP 16H06276"],"award-info":[{"award-number":["JP 16H06276"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["JP 22H049"],"award-info":[{"award-number":["JP 22H049"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["anatomypubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Developmental Dynamics"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case presentations have been reported. TRPS is characterized by sparse slow\u2010growing fine hair, a bulbous nose with tented nares, and brachydactyly with cone\u2010shaped epiphyses on the hands and feet. Growth retardation and hip dysplasia are also frequently observed, suggesting that hair and skeletal phenotypes are the major pathologies of TRPS. Several animal models have been established and studied intensively to address this rare disease. However, comprehensive treatment strategies for TRPS have not been established. In this review, we summarize TRPS pathologies and the characteristics of TRPS1 as an atypical GATA\u2010type transcription factor. We review rodent strains that have contributed to our understanding of the in vivo roles of Trps1 and discuss their validity as animal models of TRPS. We also summarize diseases that demonstrate pathologies similar to TRPS and findings in their animal models.<\/jats:p>","DOI":"10.1002\/dvdy.70082","type":"journal-article","created":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T10:56:17Z","timestamp":1758797777000},"page":"228-245","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies"],"prefix":"10.1002","volume":"255","author":[{"given":"Naoya","family":"Saeki","sequence":"first","affiliation":[{"name":"Department of Tissue and Developmental Biology Osaka University Graduate School of Dentistry  Osaka Japan"},{"name":"Division of Special Care Dentistry Osaka University Dental Hospital  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rinna","family":"Kanai","sequence":"additional","affiliation":[{"name":"Department of Tissue and Developmental Biology Osaka University Graduate School of Dentistry  Osaka Japan"},{"name":"Department of Fixed Prosthodontics and Orofacial Function Osaka University Graduate School of Dentistry  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayuri","family":"Tatsuta","sequence":"additional","affiliation":[{"name":"Department of Tissue and Developmental Biology Osaka University Graduate School of Dentistry  Osaka Japan"},{"name":"Department of Orthodontics and Dentofacial Orthopedics Osaka University Graduate School of Dentistry  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Kawaguchi","sequence":"additional","affiliation":[{"name":"Graduate School of Frontier Biosciences, Osaka University  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masatsune","family":"Itoh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kanazawa Medical University  Kahoku\u2010gun Ishikawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinsuke","family":"Ohba","sequence":"additional","affiliation":[{"name":"Department of Tissue and Developmental Biology Osaka University Graduate School of Dentistry  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2823-0881","authenticated-orcid":false,"given":"Makoto","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Tissue and Developmental Biology Osaka University Graduate School of Dentistry  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,25]]},"reference":[{"issue":"5","key":"e_1_2_9_2_1","first-page":"475","article-title":"Tricho\u2010rhino\u2010phalangeal syndrome","volume":"21","author":"Giedion A","year":"1966","journal-title":"Helv Paediatr Acta"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1148\/91.3.447"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/71717"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1086\/316926"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2015.03.002"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320190110"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0000000000000330"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1297\/cpe.25.115"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.38204"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12881\u2010017\u20100413\u20108"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2019.03.028"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2019.103830"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mgg3.1417"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAI.0000000000001056"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2022.34.2.139"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.990230"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.24953\/turkjped.2022.793"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2023.104870"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2024.104937"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12519\u2010011\u20100262\u2010z"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346\u20108138.12111"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001050051262"},{"issue":"4","key":"e_1_2_9_24_1","first-page":"348","article-title":"Facial and oral findings in trichorhinophalangeal syndrome type 1 (characteristics of TRPS 1)","volume":"3","author":"Bennett CG","year":"1981","journal-title":"Pediatr Dent"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002\u20109416(79)90140\u20104"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23147873"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1159\/000143852"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.63132"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197355040-00017"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/01241398-198603000-00002"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2012.01.011"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/01241398\u2010199505000\u201000023"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.5312\/wjo.v10.i3.145"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/children9081121"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301\u2010620x.84b5.12124"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0b013e318223b423"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2014.08.002"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.159.2.3961186"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.11.3.312"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2006.08.011"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr\u20102020\u2010237604"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.3109\/0886022X.2014.882237"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.7.1715"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1439790"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002399910012"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1013504710343"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432\u20101033.2002.03313.x"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5201094"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1017\/erm.2016.2"},{"issue":"7","key":"e_1_2_9_50_1","first-page":"915","article-title":"The function of TRPS1 in the development and differentiation of bone, kidney, and hair follicles","volume":"26","author":"Gai Z","year":"2011","journal-title":"Histol Histopathol"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1074\u20107613(00)80034\u20105"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12209"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.069971"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1003002"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1128004"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/74301"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0808324106"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2005.06.064"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2008.05.009"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2009.01.012"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097\u20100177(199801)211:1<88::AID\u2010AJA8>3.0.CO;2\u20103"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00335\u2010001\u20102115\u2010x"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.02097"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddn125"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2019.09.012"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.00324"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.02772"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2011.06.011"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/78099"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2009.04.003"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2011.01.001"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.414441"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.126.6.1211"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1038\/73488"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102443.2000.00300.x"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2007.03.011"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2003.10.154"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood\u20102006\u201001\u2010031781"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/454085"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.137596.112"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0500904102"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000002213"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379\u2010020\u201000692\u20108"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.15126"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12672\u2010010\u20100008\u20108"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41388\u2010018\u20100312\u20102"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41389\u2010018\u20100108\u20109"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.192856.112"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.07.019"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2015.349"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13058\u2010018\u20101018\u20107"},{"key":"e_1_2_9_92_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.22.24.8592-8600.2002"},{"key":"e_1_2_9_93_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.080414"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.72"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(08)60599\u20101"},{"key":"e_1_2_9_96_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32348"},{"key":"e_1_2_9_97_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20100004.2010.01434.x"},{"key":"e_1_2_9_98_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2019.00513"},{"key":"e_1_2_9_99_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534\u2010199904050\u201000015"},{"key":"e_1_2_9_100_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01657"},{"key":"e_1_2_9_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2007.10.001"},{"key":"e_1_2_9_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2014.12.039"},{"key":"e_1_2_9_103_1","doi-asserted-by":"publisher","DOI":"10.4081\/dr.2019.7853"},{"key":"e_1_2_9_104_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441\u2010012\u20101372\u20101"},{"key":"e_1_2_9_105_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.24130"},{"key":"e_1_2_9_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4773(03)00103-5"},{"key":"e_1_2_9_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2008.03.009"},{"key":"e_1_2_9_108_1","doi-asserted-by":"publisher","DOI":"10.3389\/fdmed.2022.875987"},{"key":"e_1_2_9_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2020.104735"},{"key":"e_1_2_9_110_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00223\u2010024\u201001277\u20102"},{"key":"e_1_2_9_111_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddae102"},{"key":"e_1_2_9_112_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01871379"},{"key":"e_1_2_9_113_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440\u20101673.1985.tb01685.x"},{"key":"e_1_2_9_114_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20100004.1992.tb03650.x"},{"key":"e_1_2_9_115_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k775"},{"key":"e_1_2_9_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2021.06.015"},{"key":"e_1_2_9_117_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports\u20102022\u2010105496"},{"key":"e_1_2_9_118_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.55212"},{"key":"e_1_2_9_119_1","first-page":"163","article-title":"Koala, a dominant mutation","volume":"83","author":"Ball ST","year":"1989","journal-title":"Mouse News Lett"},{"key":"e_1_2_9_120_1","first-page":"237","article-title":"Koala, Koa, is associated with an inversion on mouse chromosome 15","volume":"59","author":"Peters J","year":"1992","journal-title":"Genet Res"},{"key":"e_1_2_9_121_1","doi-asserted-by":"publisher","DOI":"10.1538\/expanim.57.73"},{"key":"e_1_2_9_122_1","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.104.031914"},{"key":"e_1_2_9_123_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI23675"},{"key":"e_1_2_9_124_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0298\u2010143"},{"key":"e_1_2_9_125_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.8.4180"},{"key":"e_1_2_9_126_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddn247"},{"key":"e_1_2_9_127_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102156\u201010\u201060"},{"key":"e_1_2_9_128_1","doi-asserted-by":"publisher","DOI":"10.1017\/s0016672300035266"},{"key":"e_1_2_9_129_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00335\u2010007\u20109015\u20107"},{"key":"e_1_2_9_130_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20103164.2008.00709.x"},{"key":"e_1_2_9_131_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20100004.1993.tb03862.x"},{"key":"e_1_2_9_132_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2014.62"},{"key":"e_1_2_9_133_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320070111"},{"key":"e_1_2_9_134_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320070110"},{"key":"e_1_2_9_135_1","doi-asserted-by":"publisher","DOI":"10.1086\/429346"},{"key":"e_1_2_9_136_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.21328"},{"key":"e_1_2_9_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0397\u2010266"},{"key":"e_1_2_9_138_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/8.9.1769"},{"key":"e_1_2_9_139_1","doi-asserted-by":"publisher","DOI":"10.1038\/78107"},{"key":"e_1_2_9_140_1","doi-asserted-by":"publisher","DOI":"10.1086\/303084"},{"key":"e_1_2_9_141_1","doi-asserted-by":"publisher","DOI":"10.1038\/78113"},{"key":"e_1_2_9_142_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.22156"},{"key":"e_1_2_9_143_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq462"},{"key":"e_1_2_9_144_1","doi-asserted-by":"publisher","DOI":"10.1038\/73495"}],"container-title":["Developmental Dynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dvdy.70082","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dvdy.70082","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dvdy.70082","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T12:10:34Z","timestamp":1773749434000},"score":1,"resource":{"primary":{"URL":"https:\/\/anatomypubs.onlinelibrary.wiley.com\/doi\/10.1002\/dvdy.70082"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,25]]},"references-count":143,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/dvdy.70082"],"URL":"https:\/\/doi.org\/10.1002\/dvdy.70082","archive":["Portico"],"relation":{},"ISSN":["1058-8388","1097-0177"],"issn-type":[{"value":"1058-8388","type":"print"},{"value":"1097-0177","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,25]]},"assertion":[{"value":"2025-02-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}