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It was found that 50% of chimeric fetuses, the proportion predicted to be XX \u2194 XY, had neither normal testes nor ovaries. Instead, ovotestes were present, with varying proportions of presumptive ovarian and testicular tissue. On day 12 the ovotestes were organized with testicular tissue in the central region and ovarian tissue at the craniad and\/or caudad poles. In the more advanced fetuses there was evidence of regression of the ovarian portion, which would account for the testes found in adults. These results are discussed in light of current theories of sex determination and differentiation and what was previously known about gonads of sex mosaics.<\/jats:p>","DOI":"10.1002\/dvg.1020080405","type":"journal-article","created":{"date-parts":[[2005,5,25]],"date-time":"2005-05-25T22:18:56Z","timestamp":1117059536000},"page":"207-218","source":"Crossref","is-referenced-by-count":13,"title":["Testes of XX \u2194 XY chimeric mice develop from fetal ovotestes"],"prefix":"10.1002","volume":"8","author":[{"given":"Michael W.","family":"Bradbury","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,2,6]]},"reference":[{"key":"e_1_2_1_2_1","unstructured":"BradburyMW(1982): \u201cPrimary Sex Determination and Gonadal Morphogenesis in the Mouse.\u201d Ph.D. Dissertation New Haven: Yale 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