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Invasive Burmese pythons (\n                    <jats:italic>Python bivittatus<\/jats:italic>\n                    ) in South Florida exemplify this challenge, as metrics based on raw removals or body size alone may not reflect demographic impacts. To address this, we introduce the Weighted Removal Index (WRI), a demographic weighting framework that prioritizes removals based on expected contributions to survival and reproduction. Using survey data from the South Florida Water Management District's Python Elimination Program, we quantified operational and environmental conditions associated with higher survey WRI, defined as the summed WRI of all pythons captured on a single survey, and evaluated three forecasting approaches: Generalized Additive Models (GAMs), Boosted Regression Trees (BRT), and Neural Networks (NN). Survey WRI was highest under waning lunar phases, when surveys were assisted, and under warmer and more humid conditions. Additionally, survey WRI was elevated on warm days early in the wet season and cool dry\u2010season days. In held\u2010out test evaluation, the NN achieved the highest balanced accuracy for predicting survey success (0.703), and the lowest error for predicting survey WRI (root mean squared error [RMSE]\u2009=\u20095.50). Contractor performance was highly heterogeneous, with contractor\u2010specific effects positively associated with mean survey WRI (\n                    <jats:italic>R<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u20090.589) and capture rate (\n                    <jats:italic>R<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u20090.596). Notably, model\u2010based predictions of survey success fell within the upper tail of the contractor capture\u2010rate distribution, indicating that near\u2010term forecasting can match the performance of the highest performing contractors. Together, demographic weighting and near\u2010term forecasting provide a practical decision\u2010support framework for guiding effort toward high\u2010impact removals in cryptic invader management.\n                  <\/jats:p>","DOI":"10.1002\/eap.70317","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T23:52:42Z","timestamp":1790034762000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prioritizing removals of a highly cryptic invasive species using machine learning and demographic weighting"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7882-4622","authenticated-orcid":false,"given":"Alexander S.","family":"Romer","sequence":"first","affiliation":[{"name":"Department of Wildlife Ecology and Conservation, Fort Lauderdale Research and Education Center University of Florida  Davie Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6743-6808","authenticated-orcid":false,"given":"Melissa A.","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Wildlife Ecology and Conservation, Fort Lauderdale Research and Education Center University of Florida  Davie Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5153-0031","authenticated-orcid":false,"given":"Sergio A.","family":"Balaguera\u2010Reina","sequence":"additional","affiliation":[{"name":"Department of Wildlife Ecology and Conservation, Fort Lauderdale Research and Education Center University of Florida  Davie Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle C.","family":"Bassis","sequence":"additional","affiliation":[{"name":"Department of Wildlife Ecology and Conservation, Fort Lauderdale Research and Education Center University of Florida  Davie Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon","family":"Welty","sequence":"additional","affiliation":[{"name":"Department of Wildlife Ecology and Conservation, Fort Lauderdale Research and Education Center University of Florida  Davie Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Kirkland","sequence":"additional","affiliation":[{"name":"South Florida Water Management District  West Palm Beach Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Peters","sequence":"additional","affiliation":[{"name":"South Florida Water Management District  West Palm Beach Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Edward F.","family":"Metzger","sequence":"additional","affiliation":[{"name":"South Florida Water Management District  West Palm Beach Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenna","family":"Cole","sequence":"additional","affiliation":[{"name":"South Florida Water Management District  West Palm Beach Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LeRoy","family":"Rodgers","sequence":"additional","affiliation":[{"name":"South Florida Water Management District  West Palm Beach Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank J.","family":"Mazzotti","sequence":"additional","affiliation":[{"name":"Department of Wildlife Ecology and Conservation, Fort Lauderdale Research and Education Center University of Florida  Davie Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Abdullayev T.2024.\u201ckerastuneR: Interface to \u201cKeras Tuner\u201d.\u201d"},{"key":"e_1_2_9_3_1","unstructured":"Allaire J. 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