{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T23:51:54Z","timestamp":1790898714001,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2002,8,23]],"date-time":"2002-08-23T00:00:00Z","timestamp":1030060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2002,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To study fracture risk in patients with anorexia nervosa (AN), bulimia nervosa (BN), or eating disorders not otherwise specified (EDNOS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Cohort study including all Danes diagnosed with AN (<jats:italic>n<\/jats:italic> = 2,149), BN (<jats:italic>n<\/jats:italic> = 1,294), or EDNOS (<jats:italic>n<\/jats:italic> = 942) between 1977 and 1998. Each patient was compared with three randomly drawn age\u2010 and gender\u2010matched control subjects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fracture risk was increased in AN after diagnosis compared to controls (incidence rate ratio: 1.98, 95% CI: 1.60\u20132.44), but not before. The increased fracture risk persisted more than 10 years after diagnosis. A significant increase in fracture risk was found before diagnosis in BN (1.31, 95% CI: 1.04\u20131.64), with a trend towards an increase after diagnosis (1.44, 95% CI: 0.93\u20132.22). EDNOS patients had a significant increase in fracture risk before (1.39, 95% CI: 1.06\u20131.81) and after diagnosis (1.77, 95% CI: 1.25\u20132.51).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The increased fracture risk many years after diagnosis indicates permanent skeletal damage. \u00a9 2002 by Wiley Periodicals, Inc. 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