{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:09:49Z","timestamp":1763035789919,"version":"3.30.2"},"reference-count":51,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2003,8,26]],"date-time":"2003-08-26T00:00:00Z","timestamp":1061856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2003,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To examine prospectively the natural course of bulimia nervosa (BN) and eating disorder not otherwise specified (EDNOS) and to test the effects of personality disorder (PD) comorbidity on the outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Ninety\u2010two female patients with current BN (<jats:italic>N<\/jats:italic>= 23) or EDNOS (<jats:italic>N<\/jats:italic>= 69) were evaluated at baseline enrollment in the Collaborative Longitudinal Personality Disorders Study (CLPS). Eating disorders (EDs) were assessed with the Structured Clinical Interview for DSM\u2010IV Axis I Disorders. Personality disorders (PDs) were assessed with the Diagnostic Interview for DSM\u2010IV PD (DIPD\u2010IV). The course of BN and EDNOS was assessed with the Longitudinal Interval Follow\u2010up Evaluation and the course of PDs was evaluated with the Follow\u2010Along version of the DIPD\u2010IV at 6, 12, and 24 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Probability of remission at 24 months was 40% for BN and 59% for EDNOS. To test the effects of PD comorbidity on course, ED patients were divided into groups with no, one, and two or more PDs. Cox proportional regression analyses revealed that BN had a longer time to remission than EDNOS (<jats:italic>p<\/jats:italic>&lt; .05). The number of PDs was not a significant predictor of time to remission, nor was the presence of Axis I psychiatric comorbidity or Global Assessment of Functioning scores. Analyses using proportional hazards regression with time\u2010varying covariates revealed that PD instability was unrelated to changes in ED.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>BN has a worse 24\u2010month course (longer time to remission) than EDNOS. The natural course of BN and EDNOS is not influenced significantly by the presence, severity, or time\u2010varying changes of co\u2010occurring PDs, co\u2010occurring Axis I disorders, or by global functioning. \u00a9 2003 by Wiley Periodicals, Inc. 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