{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T12:30:52Z","timestamp":1747657852743},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,1,29]],"date-time":"2007-01-29T00:00:00Z","timestamp":1170028800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective:<\/jats:title><jats:p>Multiple tuberculous mycobacterial infections infrequently occur in immunocompromised patients. The malnutrition resulted from anorexia nervosa may contribute to the significant impairment of immunity. The authors present a 23\u2010year\u2010old female patient initially diagnosed with anorexia nervosa.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method:<\/jats:title><jats:p>Immunological study revealed that helper T\u2010cell (CD4) and cytotoxic T\u2010cell (CD8) comprised 25 and 32%, respectively, with a CD4 to CD8 ratio of 0.78. Brain magnetic resonance imaging revealed various multiple rings enhancing lesions with edematous change in both cerebral and cerebellar hemispheres.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Open biopsy disclosed palisading epithelioid granuloma surrounded by inflamed granulation tissue. After anti\u2010tuberculous therapy for 12 months, her weight was completely restored, but multiple intracranial tuberculomas were not completely disappeared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>Disseminated tuberculous mycobacterial infections including multiple intracranial tuberculomas may be attributed to immunocompromised status in anorexia nervosa. \u00a9 2007 by Wiley Periodicals, Inc. Int J Eat Disord 2007<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.20368","type":"journal-article","created":{"date-parts":[[2007,2,2]],"date-time":"2007-02-02T18:41:24Z","timestamp":1170441684000},"page":"288-291","source":"Crossref","is-referenced-by-count":1,"title":["Disseminated tuberculosis with multiple intracerebral tuberculomas in a patient with anorexia nervosa"],"prefix":"10.1002","volume":"40","author":[{"given":"Jung Yong","family":"Ahn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Hee","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keun Su","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won Joo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,29]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"213","article-title":"Global tuberculosis incidence and mortality during 1990\u20132000","volume":"72","author":"Dolin PJ","year":"1994","journal-title":"Bull World Health Organ"},{"key":"e_1_2_1_3_2","first-page":"129","article-title":"Advances in diagnosis, treatment and prognosis of intracerebral tuberculomas in the last 50 years. 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