{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T23:41:15Z","timestamp":1788478875764,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2007,7,2]],"date-time":"2007-07-02T00:00:00Z","timestamp":1183334400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2007,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective:<\/jats:title><jats:p>To describe and discuss potential relationships between anorexia nervosa (AN) and Raynaud's phenomenon, the course and concurrent treatment of these two disorders as they appeared simultaneously, and a potential treatment modification entailed in such concurrent therapies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background:<\/jats:title><jats:p>Although Raynaud's phenomenon has been described during the course of AN, the associations and interactions between these two conditions are not clear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method:<\/jats:title><jats:p>We report the medical workup, treatment, and outcomes in a 19\u2010year old female patient who developed Raynaud's phenomenon following the onset of AN.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>After treatment with nutritional rehabilitation, counseling, and individual and group therapy, the patient's weight, eating disorder\u2010related behaviors, and attitudes improved significantly. Raynaud's related symptoms improved, following treatment with a calcium channel blocker and antiaggregant therapy. In conjunction with nutritional efforts to treat the patient's long\u2010standing amenorrhea and osteopenia, the treatment team elected to also administer estrogen hormone in addition to oral calcium and vitamin D supplementation. Since oral contraceptives are to be avoided in patients with Raynaud's phenomenon who show clinical findings suggesting connective tissue disorder, the treatment team elected to treat this patient with transdermal hormone replacement therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>The co\u2010occurrence of AN and Raynaud's phenomenon merits close and persistent follow\u2010up by a multidisciplinary team and may lead to alterations of usual therapeutic approaches. \u00a9 2007 by Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.20418","type":"journal-article","created":{"date-parts":[[2007,7,2]],"date-time":"2007-07-02T17:49:00Z","timestamp":1183398540000},"page":"762-765","source":"Crossref","is-referenced-by-count":12,"title":["Anorexia nervosa and Raynaud's phenomenon: A case report"],"prefix":"10.1002","volume":"40","author":[{"given":"Basak","family":"Yucel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayse Kubat","family":"Uzum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nese","family":"Ozbey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sevil","family":"Kamali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel","family":"Yager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,7,2]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0248-8663(05)81204-4"},{"key":"e_1_2_1_3_2","first-page":"44","volume-title":"Eating Disorders","author":"De Zwaan M","year":"1999"},{"key":"e_1_2_1_4_2","first-page":"1850","article-title":"Digital necrosis in a patient with anorexia nervosa. 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