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Effect sizes, odds ratios, and simple rates were integrated in fixed and random (mixed) effects categorical models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>From randomized controlled trials, psychotherapy and structured self\u2010help, both based on cognitive behavioral interventions, were found to have large effects on the reduction of binge eating. Regarding pharmacotherapy, mainly comprising antidepressants, randomized controlled trials revealed medium effects for the reduction of binge eating. Uncontrolled studies on weight\u2010loss treatments demonstrated moderate reductions of binge eating. Combination treatments did not result in higher effects compared with single\u2010treatment regimens. Except for weight\u2010loss treatment, none of the interventions resulted in a considerable weight reduction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion:<\/jats:title><jats:p>Psychotherapy and structured self\u2010help, both based on cognitive\u2010behavioral interventions, should be recommended as the first\u2010line treatments. \u00a9 2009 by Wiley Periodicals, Inc. 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