{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:31:34Z","timestamp":1790728294071,"version":"4.1.0"},"reference-count":49,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,12,8]],"date-time":"2010-12-08T00:00:00Z","timestamp":1291766400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>It is well known that individuals with anorexia nervosa (AN) are inhibited and over\u2010controlled. This study investigated a prefrontal\u2010cingulate network that is involved in inhibitory control.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>To avoid the confounds of malnutrition, 12 recovered (RAN) subjects were compared to 12 matched control women (CW) using a validated inhibition task (i.e., a stop signal task) during functional magnetic resonance imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Consistent with the\n                      <jats:italic>a priori<\/jats:italic>\n                      hypothesis, RAN subjects showed altered task\u2010related activation in the medial prefrontal cortex (mPFC), a critical node of the inhibitory control network. Specifically, whereas RAN and CW showed similar mPFC acitivity during trials when inhibitory demand was low (i.e., easy trials), RAN relative to CW showed significantly less mPFC activation as inhibition trials became more difficult (i.e., hard trials), suggesting a demand\u2010specific modulation of inhibitory control circuitry in RAN.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>These findings support a neural basis for altered impulse control symptoms in AN \u00a9 \u00a9 2010 by Wiley Periodicals, Inc. (Int J Eat Disord 2011; 44:1\u20138)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/eat.20750","type":"journal-article","created":{"date-parts":[[2010,2,2]],"date-time":"2010-02-02T10:50:13Z","timestamp":1265107813000},"page":"1-8","source":"Crossref","is-referenced-by-count":85,"title":["Demand\u2010specific alteration of medial prefrontal cortex response during an inhibition task in recovered anorexic women"],"prefix":"10.1002","volume":"44","author":[{"given":"Tyson A.","family":"Oberndorfer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter H.","family":"Kaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan N.","family":"Simmons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina A.","family":"Strigo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott C.","family":"Matthews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,12,8]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890423349"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617704104086"},{"key":"e_1_2_6_4_2","first-page":"255","volume-title":"Neurobiology in the Treatment of Eating Disorders","author":"Ellison AR","year":"1998"},{"key":"e_1_2_6_5_2","first-page":"113","volume-title":"AED Annual Review of Eating Disorders, Part 2","author":"Kaye W","year":"2006"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.24.1.167"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291707009877"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2004.03.001"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20225"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2002.1198"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1162\/jocn.2008.20100"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-1-2"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4927(01)00093-2"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.161.7.1238"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20203"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2008.08050775"},{"key":"e_1_2_6_17_2","unstructured":"Metropolitan Life Insurance Company. 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