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Those who showed onset of threshold\/subthreshold BN experienced greater increases in weight in the 2 years before onset of their eating disorder relative to healthy comparison participants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion:<\/jats:title><jats:p>This is the first prospective study to demonstrate that weight gain and weight loss may both increase risk for future onset of bulimic pathology. Results suggest that young women who have difficulty limiting their dietary intake are at increased risk for BN, an eating disorder characterized by loss of control over eating. \u00a9 2010 by Wiley Periodicals, Inc. 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