{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:32:20Z","timestamp":1785429140301,"version":"3.56.0"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,3,4]],"date-time":"2014-03-04T00:00:00Z","timestamp":1393891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["MH093311"],"award-info":[{"award-number":["MH093311"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["MH61836"],"award-info":[{"award-number":["MH61836"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study examined pre\u2010 and postprandial glucagon\u2010like peptide 1 (GLP\u20101) levels in women with bulimia nervosa (BN), purging disorder (PD), and non\u2010eating disorder control women to better understand whether alterations in satiation\u2010related hormones in BN may be linked to binge\u2010eating episodes or other altered ingestive behaviors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Participants included women with BN (<jats:italic>n<\/jats:italic>\u2009=\u200919), PD (<jats:italic>n<\/jats:italic>\u2009=\u200914), or controls (<jats:italic>n<\/jats:italic>\u2009=\u200914). Participants provided subjective ratings for hunger and fullness and plasma samples before and after consumption of a standardized test meal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>As expected, GLP\u20101 levels increased significantly following test meal consumption; however, participants with BN displayed significantly lower GLP\u20101 levels compared to PD and control participants both before and after consumption of the test meal. There were no significant differences between PD and control participants in GLP\u20101 levels, but individuals with PD displayed significantly higher levels of fullness throughout the test meal as compared to both control and BN participants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Our findings provide preliminary evidence that reduced GLP\u20101 levels in individuals with BN may be associated with binge\u2010eating episodes. Additionally, increased fullness in individuals with PD does not appear to be accounted for by exaggerated postprandial GLP\u20101 release. \u00a9 2014 Wiley Periodicals, Inc. 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