{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:14:59Z","timestamp":1791278099651,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,4,9]],"date-time":"2014-04-09T00:00:00Z","timestamp":1397001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Norwegian Ministry of Education and Research"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study explored the neuropsychological performance of patients diagnosed with anorexia nervosa (AN) or bulimia nervosa (BN) compared with healthy controls (HCs). An additional aim was to investigate the effect of several possible mediators on the association between eating disorders (EDs) and cognitive function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Forty patients with AN, 39 patients with BN, and 40 HCs who were comparable in age and education were consecutively recruited to complete a standardized neuropsychological test battery covering the following cognitive domains: verbal learning and memory, visual learning and memory, speed of information processing, visuospatial ability, working memory, executive function, verbal fluency, attention\/vigilance, and motor function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The AN group scored significantly below the HCs on eight of the nine measured cognitive domains. The BN group also showed inferior performance on six cognitive domains. After adjusting for possible mediators, the nadir body mass index (lowest lifetime BMI) and depressive symptoms explained all findings in the BN group. Although this adjustment reduced the difference between the AN and HC groups, the AN group still performed worse than the HCs regarding verbal learning and memory, visual learning and memory, visuospatial ability, working memory, and executive functioning.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Patients with EDs scored below the HCs on several cognitive function measures, this difference being most pronounced for the AN group. The nadir BMI and depressive symptoms had strong mediating effects. Longitudinal studies are needed to identify the importance of weight restoration and treatment of depressive symptoms in the prevention of a possible cognitive decline. \u00a9 2014 Wiley Periodicals, Inc. (Int J Eat Disord 2015; 48:397\u2013405)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/eat.22283","type":"journal-article","created":{"date-parts":[[2014,4,9]],"date-time":"2014-04-09T10:22:16Z","timestamp":1397038936000},"page":"397-405","source":"Crossref","is-referenced-by-count":73,"title":["Neuropsychological function in patients with anorexia nervosa or bulimia nervosa"],"prefix":"10.1002","volume":"48","author":[{"given":"Siri","family":"Weider","sequence":"first","affiliation":[{"name":"Department of Psychology Norwegian University of Science and Technology Trondheim Norway"},{"name":"Specialised Unit for Eating Disorder Patients Department of Psychiatry Levanger Hospital, Health Trust Nord\u2010Tr\u00f8ndelag Levanger Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marit S\u00e6b\u00f8","family":"Indredavik","sequence":"additional","affiliation":[{"name":"Regional Centre for Child and Youth Mental Health and Child Welfare Norwegian University of Science and Technology Trondheim Norway"},{"name":"Department of Child and Adolescent Psychiatry St. Olav's University Hospital Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stian","family":"Lydersen","sequence":"additional","affiliation":[{"name":"Regional Centre for Child and Youth Mental Health and Child Welfare Norwegian University of Science and Technology Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Knut","family":"Hestad","sequence":"additional","affiliation":[{"name":"Department of Psychology Norwegian University of Science and Technology Trondheim Norway"},{"name":"Division of Mental Health Innlandet Hospital Trust Hamar Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,4,9]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"107","article-title":"Neuropsicologia dos transtornos alimentares: revisao sistematica da literatura","volume":"26","author":"Duchesne M","year":"2004","journal-title":"[Neuropsychology of eating disorders: A systematic review of the literature]. 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