{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:55:08Z","timestamp":1791334508957,"version":"4.3.1"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,8,18]],"date-time":"2014-08-18T00:00:00Z","timestamp":1408320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["K23 MH76195"],"award-info":[{"award-number":["K23 MH76195"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01 MH079397"],"award-info":[{"award-number":["R01 MH079397"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012666","name":"Global Foundation for Eating Disorders","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012666","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Inadequate intake and preference for low\u2010calorie foods are salient behavioral features of Anorexia Nervosa (AN). The neurocognitive mechanisms underlying pathological food choice have not been characterized. This study aimed to develop a new paradigm for experimentally modeling maladaptive food choice in AN.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Individuals with AN (<jats:italic>n<\/jats:italic>\u2009=\u200922) and healthy controls (HC, <jats:italic>n<\/jats:italic>\u2009=\u200920) participated in a computer\u2010based Food Choice Task, adapted for individuals with eating disorders. Participants first rated 43 food images (including high\u2010fat and low\u2010fat items) for Healthiness and Tastiness; an item rated neutral on both blocks was then selected as the Reference item. On each of 42 subsequent trials participants were asked to choose between the food item presented and the Reference item.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The AN group was less likely to choose high\u2010fat foods relative to HC, as evidenced both in multilevel logistic regression (<jats:italic>z<\/jats:italic>\u2009=\u20092.59, <jats:italic>p<\/jats:italic>\u2009=\u2009.009) and ANOVA (<jats:italic>F<\/jats:italic>(1,39)\u2009=\u20097.80, <jats:italic>p<\/jats:italic>\u2009=\u2009.008) analyses. Health ratings influenced choice significantly more in AN relative to HC (<jats:italic>z<\/jats:italic>\u2009=\u20092.7, <jats:italic>p<\/jats:italic>\u2009=\u2009.006), and were more related to Taste among AN (<jats:italic>\u03c7<\/jats:italic><jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"#eat22345-bib-0002\"\/>\u2009=\u20094.10, <jats:italic>p<\/jats:italic>\u2009=\u2009.04). Additionally, taste ratings declined with duration of illness (<jats:italic>r<\/jats:italic>\u2009=\u2009\u2212.50, <jats:italic>p<\/jats:italic>\u2009=\u2009.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The Food Choice Task captures the preference for low\u2010fat foods among individuals with AN. The findings suggest that the experience of tastiness changes over time and may contribute to perpetuation of illness. By providing an experimental quantitative measure of food restriction, this task opens the door to new experimental investigations into the cognitive, affective, and neural factors contributing to maladaptive food choices characteristic of AN. \u00a9 2014 Wiley Periodicals, Inc. 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