{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:28:26Z","timestamp":1790710106600,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,5,27]],"date-time":"2015-05-27T00:00:00Z","timestamp":1432684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Institute of Health grant (PI)","award":["T32MH076694"],"award-info":[{"award-number":["T32MH076694"]}]},{"name":"Swedish Council for Working Life"},{"name":"Social Research and the Swedish Research Council"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study explored the cross\u2010sectional and predictive effect of drive for thinness and\/or negative affect scores on the development of self\u2010reported anorexia nervosa (AN) and bulimia nervosa (BN).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>K\u2010means were used to cluster the Eating Disorder Inventory\u2010Drive for Thinness (DT) and Child Behavior Checklist Anxious\/Depressed (A\/D) scores from 615 unrelated female twins at age 16\u201317. Logistic regressions were used to assess the effect of these clusters on self\u2010reported eating disorder diagnosis at ages 16\u201317 (<jats:italic>n<\/jats:italic>\u2009=\u2009565) and 19\u201320 (<jats:italic>n<\/jats:italic>\u2009=\u2009451).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>DT and A\/D scores were grouped into four clusters: Mild (scores lower than 90th percentile on both scales), DT (higher scores only on DT), A\/D (higher scores only on A\/D), and DT\u2010A\/D (higher scores on both the DT and A\/D scales). DT and DT\u2010A\/D clusters at age 16\u201317 were associated cross\u2010sectionally with AN and both cross\u2010sectionally and longitudinally with BN. The DT\u2010A\/D cluster had the highest prevalence of AN at follow\u2010up compared with all other clusters. Similarly, an interaction was observed between DT and A\/D that predicted risk for AN.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Having elevated DT and A\/D scores may increase risk for eating disorder symptomatology above and beyond a high score on either alone. Findings suggest that cluster modeling based on DT and A\/D may be useful to inform novel and useful intervention strategies for AN and BN in adolescents. \u00a9 2015 Wiley Periodicals, Inc. 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