{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:10:28Z","timestamp":1788999028392,"version":"build-2803163510"},"reference-count":79,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T00:00:00Z","timestamp":1455494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Eating disorders that are associated with purging behaviors are complicated by frequent blood electrolyte and acid\u2010base abnormalities. Herein, we review the major electrolyte and acid\u2010base abnormalities and their treatment methods. The body of rigorous, eating disorder\u2010specific literature on this topical area is not robust enough to perform a systematic review as defined by PRISMA guidelines. Therefore, a qualitative review of mostly medical literature was conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Hypokalemia, hyponatremia, and sodium chloride\u2010responsive metabolic alkalosis are the most common serum changes that occur as a result of purging behaviors. They vary depending on the mode and frequency of purging behaviors. They can all potentially cause dangerous medical complications and are in need of definitive medical treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Eating disorders that are associated with purging behaviors are associated with a number of electrolyte and acid\u2010base changes which are complex in their origin, documented to be medically dangerous and this definitive treatment is necessary to help achieve a successful treatment outcome, and in need of definitive treatment as described herein.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/eat.22503","type":"journal-article","created":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T06:35:35Z","timestamp":1455518135000},"page":"311-318","source":"Crossref","is-referenced-by-count":42,"title":["Electrolyte and acid\u2010base abnormalities associated with purging behaviors"],"prefix":"10.1002","volume":"49","author":[{"given":"Philip S.","family":"Mehler","sequence":"first","affiliation":[{"name":"Eating Recovery Center of Denver Denver Colorado"},{"name":"ACUTE, Denver Health Denver Colorado"},{"name":"University of Colorado School of Medicine Denver Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristine","family":"Walsh","sequence":"additional","affiliation":[{"name":"Eating Recovery Center of Denver Denver 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