{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T06:03:57Z","timestamp":1774937037446,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,11,6]],"date-time":"2017-11-06T00:00:00Z","timestamp":1509926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100005310","name":"Klarman Family Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005310","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Previous studies evaluating the association between early childhood adversities and eating disorders have yielded conflicting results. The aim of this study is to examine the association between a range of adversities and risk of anorexia nervosa (AN), bulimia nervosa (BN), and eating disorder not otherwise specified (EDNOS) in 495,244 women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>In this nationwide, register\u2010based cohort study, nine types of early childhood adversity (family disruption, residential instability, placement in out\u2010of\u2010home care, familial death, parental somatic illness, parental psychiatric illness, parental disability, severe parental criminality, and parental substance use disorder) were defined and exposure during the first 6\u00a0years of life was determined. Hazard ratios for eating disorders were calculated using Cox regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Few adversities were significantly associated with AN, and for each, the presence of the adversity was associated with lower risk for AN. BN, and EDNOS were positively associated with several types of adversities. AN rates were unchanged or reduced by up to 54% by adversities, whereas rates of BN and EDNOS were unchanged or increased by adversities by up to 49 and 89%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Our findings indicate that childhood adversities appear to be associated with an increased risk of BN and in particular EDNOS, whereas they seem to be either unassociated or associated with a decreased risk of AN.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.22798","type":"journal-article","created":{"date-parts":[[2017,11,6]],"date-time":"2017-11-06T08:24:55Z","timestamp":1509956695000},"page":"1404-1412","source":"Crossref","is-referenced-by-count":43,"title":["Early childhood adversities and risk of eating disorders in women: A Danish register\u2010based cohort study"],"prefix":"10.1002","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0385-1017","authenticated-orcid":false,"given":"Janne Tidselbak","family":"Larsen","sequence":"first","affiliation":[{"name":"National Centre for Register\u2010based Research, Aarhus BSS Aarhus University Aarhus Denmark"},{"name":"Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH) Aarhus University Aarhus Denmark"},{"name":"Centre for Integrated Register\u2010based Research (CIRRAU) Aarhus University Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trine","family":"Munk\u2010Olsen","sequence":"additional","affiliation":[{"name":"National Centre for Register\u2010based Research, Aarhus BSS Aarhus University Aarhus Denmark"},{"name":"Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH) Aarhus University Aarhus Denmark"},{"name":"Centre for Integrated Register\u2010based Research (CIRRAU) Aarhus University Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia M.","family":"Bulik","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of North Carolina at Chapel Hill Chapel Hill North Carolina"},{"name":"Department of Nutrition University of North Carolina at Chapel Hill Chapel Hill North Carolina"},{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura M.","family":"Thornton","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of North Carolina at Chapel Hill Chapel Hill North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne Vinkel","family":"Koch","sequence":"additional","affiliation":[{"name":"Mental Health Centre for Child and Adolescent Psychiatry Copenhagen Region Copenhagen Denmark"},{"name":"Institute of Clinical Medicine, Faculty of Health Sciences University of Copenhagen Copenhagen 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